Abstract Background: Rheumatoid arthritis is a chronic autoimmune disease that leads to severe disability and requires improved therapeutic strategies to optimize anti-inflammatory treatment. This study aimed to address this challenge by…

It is evident that the morning symptoms of rheumatoid arthritis (RA) are linked to the circadian abnormal increase in night inflammation, favoured by inadequate cortisol secretion under conditions of active disease. Therefore,…

Abstract Vesicular systems have demonstrated efficacy in the management of Rheumatoid Arthritis (RA). This study explores the synergistic effect of edge-activated ethosomal gel to enhance the transdermal delivery of Curcumin (CUR) and…

Abstract Nanotechnology has rapidly become a viable instrument for investigating innovative methods, ranging from properly identifying many disorders to treating intricate medical situations. Due to their adjustable surface qualities and…

Abstract Hydrogels have gained attention in drug delivery systems for their ability to encapsulate nanoparticles, providing sustained and targeted release. In this study, polymeric nanoparticles (NPs) of aceclofenac (ACE) were loaded…

Rheumatoid arthritis (RA) is a joint-destructive autoimmune disease that severely affects joint function. Despite the variability of treatment protocols, all of them are associated with severe side effects that compromise patient…

Rheumatoid arthritis (RA) is a systemic autoimmune disease manifested by chronic joint inflammation leading to severe disability and premature mortality. With a global prevalence of about 0.3%–1% RA is 3–5 times more prevalent in women than…

Hydrogels in Drug Delivery See the new book, edited by Alejandro J. Paredes, Garry Laverty, Eneko Larrañeta, Ryan F. Donnelly. It covers the fundamental mechanisms of drug delivery from a hydrophilic matrix, breaks down interconnections…