Low aqueous solubility of drug candidates is an ongoing challenge and pharmaceutical manufacturers pay close attention to amorphization (AMORP) technology to improve the solubility of drugs that dissolve poorly. Amorphous drug typically…

See in the following the overview on the usage fields of polyamino acids and the service spectrum of PMC Isochem as CDMO in this area: Why PolyAmino Acids - PAA Functional Excipients Biodegradable Polymers Drug Delivery…

Block copolymers and their related structure-performance relationships for controllable drug delivery have gained much attention recently. In this work, multibranched PEO-PPO copolymer M904 was synthesized, which had the same PEO and PPO …

Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered the best choice for pediatric use, due to their great ease of administration and dose-adaptability.…

Why a PAA based delivery technology? Growing interest for advanced biomedicines! Polyamino acids (PAAs)-based materials have gained much attention in the field of biomedicine as they demonstrate remarkable biocompatibility and…

Press release -  Contact: Patti Griggs 856-533-1870 PMC Isochem announces today that it is accelerating the strategic development and manufacture of polyamino acids (PAA) as functional excipients used in complex formulations and drug…

Background The use of amino acids as excipients is a promising approach to improve the physical stability and powder dispersibility of spray-dried powders for inhalation. Objectives The aim of this study was to investigate the…

Vitamin E TPGS, a water soluble derivative of natural Vitamin E, is a multirole excipient for pharmaceutical drug delivery innovation. Vitamin E TPGS is a non-ionic surfactant used as: solubilizer of poorly soluble drugs…

Orally disintegrating tablets (ODTs) attract a great attention as this easy swallowing dosage form often improves patient compliance. In the current work, orally disintegrating tablets comprising mannitol, polyvinylpyrrolidone (PVP) and an…