PharSQ Spheres – Calcium Phospate Starter Pellets
Drug layering on starter pellets is a standard technology to achieve multiparticulate dosage forms. The most widely used are still sugar spheres / non-pareils but also neutral pellets made of microcrystalline cellulose such as Cellets are applied. Although not a lot of new starter pellets have come to the market there is always some movement for specific needs such as tartaric acid pellets as functional starter pellets to enhance the solubility of weakly basic drugs in extended release formulations by pH modification.
PharSQ® Spheres CM are unique starter pellets based on calcium-phosphate combining interesting characteristics for a starter pellets such as:
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- High density
- High compatibility
- Low moisture content
- High mechanical strength
- Highly spherical
- Poorly soluble in water
- Neutral pH
See more in this article on Budenheim PharSQ Spheres CM pellets