Search Result for 'Posaconazole'

Abstract Purpose Posaconazole (PSZ) is BCS class-II drug that displays variable bioavailability upon oral administration due to extremely low and ...

use of the technology as general formulation approach (Figure 3). Figure 3. Particle size distribution of model APIs atenolol (ATN), ...

in gastric conditions and unstabilized supersaturated solutions prone to precipitation at neutral pH. This work examines the release mechanisms of ...

to investigate two commonly used processing methods, hot-melt extrusion (HME) and spray drying, and their impact on drug bioperformance. The ...

In this work, tartaric acid (TAP) and microcrystalline cellulose (CEL) spheres were chosen as examples of functional and inert beads, ...

Merck 2001 Kaletra® Ritonavir/lopinavir PVP-VA64 Tablet Abbott 2007 Norvir® Ritonavir PVP-VA64 Tablet Abbott 2010 Onmel® Itraconazole HPMC Tablet Merz 2010 ...

°C) – AL 320 – – SBEβCD Water (25 °C) – AL 324.98 – 0.741 HPγCD Water (25 °C) – ...

of amorphous solid dispersions (ASDs). In this study, we turn our attention to evaluating drug release behavior from ALC-coated ASDs, ...

II Spray drying Hypromellose acetate succinate Vertex 2011 Zelboraf Vemurafenib IV Solvent/anti-solvent precipitation Hypromellose Roche 2011 Kalydeco Ivacaftor II Spray ...

represent rich microenvironment formed at the surface of the drug substance and this leads to improved dissolution rate. No defined ...