Solids

In spite of the major advantages that the liquisolid technology offers, particularly in tackling poor bioavailability of poorly water-soluble drugs...

The most important properties of promising drug candidates for oral dosage form are aqueous solubility and intestinal permeability. Over 40%...

Hydroxypropyl methylcellulose (HPMC) is a hydrophilic retarding-release polymer with the limited application in hot melt extrusion (HME) due to its...

This chapter describes the application of lactose as excipient in the pharmaceutical industry. About 60%–70% of pharmaceutical dosage forms contain...

Modified-release oral dosage forms are commonly used in pharmaceutics to delay or sustain the release of drugs. Nowadays, they are...

This work estimates for the first time critical points in combined matrices containing varying concentrations of the hydrophilic polymer Hydroxypropyl...

The potential of the polyampholytic and polyelectrolytic starch compounds as excipients for drug controlled release was investigated using various tracers...

Thermoplastic polyurethanes (TPU) are block copolymers utilized in a wide variety of applications due to their superior characteristics as resistance,...

The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt extrusion (HME) is briefly reviewed. A systematic step-by-step approach is...

Ability to encapsulate, release and ensure effective protection of peptides in the gastrointestinal tract Peptides are rarely orally administrated due...