1 00:00:00,000 --> 00:00:03,000 How do we get denser granules? 2 00:00:03,000 --> 00:00:05,680 What is the mechanism that leads to denser granules 3 00:00:05,680 --> 00:00:07,680 as compared to spray drying? 4 00:00:07,680 --> 00:00:10,480 Could you compare mechanism that occurs in spray drying 5 00:00:10,480 --> 00:00:14,400 versus fluid bed to yield lighter and denser granules? 6 00:00:14,400 --> 00:00:18,400 Yes, in the in the spray drying you have 7 00:00:18,400 --> 00:00:22,120 a unit which is a quite high like a 8 00:00:22,120 --> 00:00:23,880 fluid bed a very high tower. 9 00:00:23,880 --> 00:00:27,320 You have a spray nozzle on top of the tower. 10 00:00:27,320 --> 00:00:32,040 You spray in and the particles, the tiny particles 11 00:00:32,040 --> 00:00:34,360 they are leaving the unit within seconds. 12 00:00:34,360 --> 00:00:36,040 So that's the reason why 13 00:00:36,040 --> 00:00:38,440 you get very tiny particles, 14 00:00:38,440 --> 00:00:40,360 you cannot directly compress. 15 00:00:40,360 --> 00:00:47,560 In our technologies we are to some degree spray drying, 16 00:00:47,560 --> 00:00:53,240 but we also agglomerate the particles with each other. 17 00:00:53,240 --> 00:00:57,800 So we get larger granules which are having 18 00:00:57,800 --> 00:01:00,600 due to their granual character 19 00:01:00,680 --> 00:01:04,040 higher or lower bulk density 20 00:01:04,040 --> 00:01:08,320 We can control that by applying the 21 00:01:08,320 --> 00:01:10,640 feasible processing parameters.