Capsules are a popular dosage form in the pharmaceutical industry because they provide an easy and convenient way to administer medications, offering precise dosage control. They can be formulated to contain a variety of active ingredients, including powders, liquids, and pellets, and can also be designed for immediate or extended release. Capsules protect sensitive drugs from environmental factors like light and air, enhancing drug stability and patient adherence.
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Capsules
Tailoring the release of highly loaded amorphous solid dispersions via additive manufacturing
Abstract
In the last decades, tremendous improvements have been made in enhancing the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Lately, their customisation potential has become a reality through filament-based 3D-printing (3DP). Highly loaded oral amorphous solid…
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Design, Characterization, and Evaluation of Solid-Self-Nano-Emulsifying Drug Delivery of Benidipine…
Abstract
The main purpose of this study was to design and develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) for the oral administration of benidipine (BD) and telmisartan (TEL) using the adsorption method with eucalyptus oil, Transcutol P, and Kolliphor EL via the Box–Behnken…
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Oral pH-Sensitive Solid Self-Microemulsion of Norcantharidin Wrapped in Colon-Coated Capsule for…
Abstract
Due to the poor solubility, permeability, stability and tumor-targeting ability of norcantharidin (NCTD), currently commercially available NCTD formulations require patients to take the medicine more frequently. Moreover, the formulation of NCTD themselves have certain toxicity, thus…
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Sallyso – Croscarmellose Sodium (CCS) by GANGWAL Healthcare
GANGWAL Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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Soluplus®-Based Pharmaceutical Formulations: Recent Advances in Drug Delivery and Biomedical…
Abstract
Poor water solubility remains a significant challenge in the pharmaceutical industry that limits the therapeutic efficacy and bioavailability of many active pharmaceuticals. Soluplus® (SLP), an amphiphilic graft copolymer made of polyethylene glycol, polyvinyl caprolactam, and polyvinyl…
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Evaluation of Permeability, Safety, and Stability of Nanosized Ketoprofen Co-Spray-Dried with…
Abstract
Pulmonary drug delivery presents a promising approach for managing respiratory diseases, enabling localized drug deposition and minimizing systemic side effects. Building upon previous research, this study investigates the cytotoxicity, permeability, and stability of a novel carrier-free…
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Bedaquiline loaded Soluplus® Micelles for Improving Solubility and Intestinal Permeability:…
Abstract
Oral delivery of bedaquiline is the preferred route of drug delivery in the treatment of multidrug-resistant tuberculosis, although its poor bioavailability leads to poor patient compliance. To overcome this problem, we have prepared bedaquiline loaded Soluplus® micelles to improve the…
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Salcaprozate-based ionic liquids for GLP-1 gastric delivery: A mechanistic understanding of in vivo…
Abstract
Oral delivery of peptides requires formulations with high concentrations of permeation enhancer (PE) to promote absorption, and often necessitates fasting time between dosing and food ingestion. Improved formulations promoting a more rapid absorption would increase convenience of use but…
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Advancing medication compounding: Use of a pharmaceutical 3D printer to auto-fill minoxidil capsules…
Abstract
Compounding medications in pharmacies is a common practice for patients with prescriptions that are not available commercially, but it is a laborious and error-prone task. The incorporation of emerging technologies to prepare personalised medication, such as 3D printing, has been delayed…
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Applications of Polysorbates – by KLK Kolb
KLK Kolb excipients, marketed under the Hedjuvan brand, are all produced at the Hedingen facility in Switzerland. These versatile excipients find extensive use in human, veterinary and biopharmaceutical industry. As surfactants, they play a crucial role in surface-to-surface interactions, including…
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