Artificial Sweeteners

by Eccles, R. What is the Role of Over 100 Excipients in Over the Counter (OTC) Cough Medicines?. Lung (2020). https://doi.org/10.1007/s00408-020-00390-x Most medicines are white bitter powders that are formulated as tablets and capsules but cough medicines are an exception where the taste and…
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Pediatric population is a diverse group comprising of different subgroups. The use of unlicensed and off-label medicines for treating children is widespread due to the non-availability of suitable dosage forms for this age group. Although the physiological differences related to the diverse age…
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Taste is a crucial factor that determines the palatability of the oral dosage form and patient compliance. Objective The aim of this work was to evaluate the organoleptic excipients in oral antibiotics for pediatric use marketed in Brazil. Methods The information was obtained from the…
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Granules with superior fluidity and low moisture absorption are ideal for tableting and capsule filling. Melt granulation as a solvent-free technology has attracted increasing interest for the granulation of moisture-sensitive drugs. The objective of the present study was to develop a…
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This thesis has focused on the study of pharmaceutical cocrystal production, and the impact of introducing an excipient into the manufacturing process. Cocrystals of sulfadimidine (SDM) and 4-aminosalicylic acid (4ASA) were formed in the presence of an excipient by spray drying and spray coating,…
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Silymarin (SLM) is a hepatoprotective herbal drug characterized by low aqueous solubility and, consequently, low oral bioavailability. The objective of this study was to enhance the physiochemical properties of SLM, through preparation and optimization of lyophilized nanosuspension tablets (LNTs).…
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Despite being the most essential nutrient, water is commonly forgotten in the fields of pharmacy and nutrition. Hydration status is determined by water balance (the difference between water input and output). Hypohydration or negative water balance is affected by numerous factors, either internal…
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Implication of Quantitative Selection of Each Excipient in Product Development Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
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The aim of this study was to prepare and evaluate Ibuprofen (IBU) solid dispersion tablets with improved dissolution and less sticking using Porous Calcium Silicate (PCS). Solid dispersion granules were prepared using water-based solid dispersion and water-retained PCS with the wet granulation…
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