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Abstract This study explores the development of a self-nanoemulsifying drug delivery system (SNEDDS) to enhance the biopharmaceutical profile of lornoxicam,...

Abstract Mucopolysaccharidosis type I (MPS-I) is a rare, multisystemic lysosomal storage disease (LSD) caused by mutations in the IDUA gene, which encodes...

Abstract BACKGROUND The pediatric drug development landscape has experienced major shifts, largely in response to legislative and regulatory initiatives. However,...

FROM CHALLENGE TO TRIUMPH Formulating high‑dose, poorly compressible APIs like Diosmin is challenging due to their fine particle size, irregular...

Abstract Oxidation represents a key pathway for the chemical degradation of therapeutic monoclonal antibodies (mAbs), and chemical liabilities such as...

Abstract Propolis is a widely studied natural raw material, the composition of which varies depending on the plant origin, harvest...

Abstract Objective The goal of this study was to create and optimize a topical cream based on cubosomes for improved...

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

FROM CHALLENGE TO TRIUMPH MUPS tablet compression is challenging due to the fragility of coated pellets, which are prone to...

What are “enteric coated” capsules and why are they used? Enteric coating refers to a dosage form (e.g. capsule) of...