Surfactants

Abstract Lipid-based drug delivery systems are very promising in addressing critical medical needs associated with cancer because they are able to enhance the efficacy of the therapeutic agents loaded in. Yet, their transferability from bench to bedside is still a challenge as it hits many…
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Abstract Oral drug administration is the preferred route for pharmaceuticals, accounting for ~90% of the global pharmaceutical market due to its convenience and cost-effectiveness. This study provides a comprehensive scientific and technological analysis of the latest advances in oral dosage forms…
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Abstract Schistosomiasis, a parasitic disease affecting around 250 million people globally, primarily children, necessitates the urgent development of pediatric praziquantel formulations, as outlined in the WHO neglected tropical diseases roadmap 2021–2030. We developed a low-cost PZQ…
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Abstract Solid lipid microparticles (SLMs) are multi-compartment lipid drug carriers that can be used in various forms via many routes of administration, primarily to obtain prolonged release, protect the drug substance or mask its taste. It is practically impossible to theoretically predict the…
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Abstract Pharmaceutical excipients such as P-glycoprotein inhibitors can also increase the solubility and affinity of drugs to the intestinal membrane, enhance paracellular pathways and endocyte uptake, and activate lymph transport pathways, thereby increasing the bioavailability of oral drugs.…
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AQUAPOL Thickening and gelling agent The AQUAPOL line of “Acrylates polymers” is a synthetic high molecular weight cross-linked water-soluble polymer of acrylic acid. The cosmetic, pharmaceutical, and home industries all use it extensively. It comes as a liquid or powder and is soluble in water,…
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Abstract Purpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility and being a substrate of P-glycoprotein (P-gp). A solid self-microemulsifying drug delivery system of relugolix (RLGL-S-SMEDDS) was prepared and evaluated in vitro and…
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Abstract Three-dimensional printing is promising in the pharmaceutical industry for personalized medicine, on-demand production, tailored drug loading, etc. Pressure-assisted microsyringe (PAM) printing is popular due to its low cost, simple operation, and compatibility with heat-sensitive drugs…
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AQUAPOL Thickening and gelling agent The AQUAPOL line of “Acrylates polymers” is a synthetic high molecular weight cross-linked water-soluble polymer of acrylic acid. The cosmetic, pharmaceutical, and home industries all use it extensively. It comes as a liquid or powder and is soluble in water,…
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Abstract Background and Purpose Liquid self-nanoemulsifying drug delivery systems (SNEDDS) face challenges related to stability, handling, and storage. In particular, lipophilic and unstable drugs, such as ramipril (RMP) and thymoquinone (THQ), face challenges in oral administration due to poor…
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