Controlled Release Excipient

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract Non-viral nanocarriers are increasingly adopted as safer alternatives to viral vectors for gene delivery, enabling scalability and improved manufacturability....

THE STRATEGIC SHIFT IN ORAL DRUG DELIVERY THE STRATEGIC SHIFT IN ORAL DRUG DELIVERY Oral administration remains the gold standard...

Abstract Poloxamer-based hydrogels, composed of thermoreversible triblock copolymers, are promising drug delivery systems due to their ability to transition from...

Abstract Extended-release (ER) oral formulations provide therapeutic and practical benefits for pediatric patients by minimizing fluctuations in systemic exposure, reducing...

Abstract Background: Rebamipide (REB) is a poorly water-soluble drug with limited ocular bioavailability, necessitating advanced delivery strategies for sustained therapy in...

Abstract Purpose Cabazitaxel (CBZ) is a semi-synthetic anti-cancer drug and belongs to BCS class IV category with poor water solubility...

Abstract Background/Objectives: Rebamipide is a gastroprotective agent with poor aqueous solubility and rapid gastrointestinal clearance, leading to reduced therapeutic efficiency. This...

Abstract The rapid development of artificial intelligence (AI) and the increasing demand for the modernization of Chinese herbal medicine (CHM)...

Abstract Aqueous colloidal dispersions of water-insoluble polymers (APDs) —commonly referred to as pharmaceutical latexes or pseudolatexes— are extensively employed in...