Drug Carrier excipients enhance and interact with the properties of active pharmaceutical ingredients (APIs).
Pharma Excipients
Drug Carrier
The role of mechanical properties in DPI carriers
Introduction
Aerodynamic performance of interactive blends depends on mixing time/energy
Leading hypothesis assumes the effect of so called press-on-forces (i.e deformation of particles during mixing)
Mechanical properties of particles should predict the behaviour of fine particle…
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Tailored Sticky Solutions: 3D-Printed Miconazole Buccal Films for Pediatric Oral Candidiasis
In this research, 3D-printed antifungal buccal films (BFs) were manufactured as a potential alternative to commercially available antifungal oral gels addressing key considerations such as ease of manufacturing, convenience of administration, enhanced drug efficacy and suitability of paediatric…
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MIGLYOL® 812 N & IMWITOR® 742 – Product Spotlights
We invite you to read the below product spotlights of IOI Oleochemicals.
IMWITOR® 742
Chemical Description / Monograph Name:
Glyceryl Mono and Dicaprylocapapate according to Ch.P.;
Registration number: F20220000443
Glycerol Monocaprylocaprate, Type I, according to Ph. Eur. also…
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Carrier Systems for Advanced Drug Delivery: Improving Drug Solubility/Bioavailability and…
Abstract
The disadvantages of some conventional drugs, including their low bioavailability, poor targeting efficiency, and important side effects, have led to the rational design of drug delivery systems. In particular, the introduction of drug delivery systems is a potential approach to enhance…
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Application of Liquisolid Pellets Technology for Improving Dissolution of Posaconazole: A DoE Based…
Abstract
Purpose
Posaconazole (PSZ) is BCS class-II drug that displays variable bioavailability upon oral administration due to extremely low and pH-dependent solubility.
Method
The present investigation was aimed to formulate and evaluate liquisolid pellets of PSZ for improving its…
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Shin-Etsu AQOAT® – Enteric coating polymer and solid dispersion carrier
Shin-Etsu supplies the various excipients for pharmaceutical industry. Let us introduce you Shin-Etsu AQOAT® Hypromellose acetate succinate (HPMCAS, NF, JP), an enteric coating material that can be used in aqueous or organic media.
Hypromellose is a non-toxic material which has been used in…
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Investigating the Effectiveness of Different Porous Nanoparticles as Drug Carriers for Retaining the…
Abstract
Pinosylvin monomethyl ether (PsMME) is a natural compound known for its valuable bioactive properties, including antioxidant and anti-inflammatory effects. However, PsMME’s susceptibility to photodegradation upon exposure to ultraviolet (UV) radiation poses a significant limitation to its…
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The most recent advances in liquisolid technology: Perspectives in the pharmaceutical industry
Abstract
Hydrophobic drugs exhibit altered bioavailability and pose other challenges at an industrial level due to their poor solubility and dissolution rates. In addition, poor flowability, compressibility, complex dosing schedules, and light-sensitivity problems associated with hydrophobic…
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Topical co-delivery of tacrolimus and calcipotriol loaded nanostructured lipid carrier: a potential…
The focus of this study was to develop a Vitamin-D3 (Calcipotriol)-based Tacrolimus (TAC)-loaded nanostructured lipid carrier (NLC) for topical application to treat psoriasis. The sonication technique followed by melt emulsification was used to formulate TAC-NLC, in which Precirol ATO-5,…
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Additive Manufacturing in Pharmaceuticals – Part 3
Additive Manufacturing in Pharmaceuticals
See the new book, edited by Dr. Subham Banerjee, Ph.D., Associate Professor in the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Guwahati, Assam, India.
Description: This book presents the different…
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