Drug Carrier excipients enhance and interact with the properties of active pharmaceutical ingredients (APIs).
Pharma Excipients
Drug Carrier
Investigating the Effectiveness of Different Porous Nanoparticles as Drug Carriers for Retaining the…
Abstract
Pinosylvin monomethyl ether (PsMME) is a natural compound known for its valuable bioactive properties, including antioxidant and anti-inflammatory effects. However, PsMME’s susceptibility to photodegradation upon exposure to ultraviolet (UV) radiation poses a significant limitation to its…
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The most recent advances in liquisolid technology: Perspectives in the pharmaceutical industry
Abstract
Hydrophobic drugs exhibit altered bioavailability and pose other challenges at an industrial level due to their poor solubility and dissolution rates. In addition, poor flowability, compressibility, complex dosing schedules, and light-sensitivity problems associated with hydrophobic…
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Topical co-delivery of tacrolimus and calcipotriol loaded nanostructured lipid carrier: a potential…
The focus of this study was to develop a Vitamin-D3 (Calcipotriol)-based Tacrolimus (TAC)-loaded nanostructured lipid carrier (NLC) for topical application to treat psoriasis. The sonication technique followed by melt emulsification was used to formulate TAC-NLC, in which Precirol ATO-5,…
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Additive Manufacturing in Pharmaceuticals – Part 3
Additive Manufacturing in Pharmaceuticals
See the new book, edited by Dr. Subham Banerjee, Ph.D., Associate Professor in the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Guwahati, Assam, India.
Description: This book presents the different…
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Elucidation of the using condition and working mechanism of tertiary lactose in dry powder…
Tertiary lactose has been shown to improve aerosolization performance of carrier-based dry powder inhalation formulations. The working mechanism of the tertiary lactose, however, is still unclear, even the optimal working condition of the lactose fines. Two strategies to incorporate the tertiary…
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Development and bioequivalence of 3D-printed medication at the point-of-care: bridging the gap…
Personalized medicine is currently hampered by the lack of flexible drug formulations. Especially for pediatric patients, manual compounding of personalized drug formulations by pharmacists is required. 3D printing of medicines, which enables small-scale manufacturing at the point-of-care, can…
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Orally disintegrating drug carriers for paediatric pharmacotherapy
Non-compliance, dosing inaccuracy, choking risk, flavour, and instability, are some of the issues associated with paediatric, oral dosage forms — tablets, capsules, solutions, and suspensions. Orally disintegrating drug carriers, a dosage form with growing interest, are thought to overcome several…
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Incorporating a Lipophilic Disulfide-Bridged Linoleic Prodrug into a Self-Microemulsifying Drug…
The oral absorption of paclitaxel (PTX) is restricted by poor solubility in the gastrointestinal tract (GIT), low permeability, and high first-pass metabolism. Lipid carriers, such as a self-microemulsifying drug delivery system (SMEDDS), have been deemed as promising vehicles for promoting oral…
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New Development in Understanding Drug–Polymer Interactions in Pharmaceutical Amorphous Solid…
Pharmaceutical amorphous solid dispersions (ASDs) represent a widely used technology to increase the bioavailability of active pharmaceutical ingredients (APIs). ASDs are based on an amorphous API dispersed in a polymer, and their stability is driven by the presence of strong intermolecular…
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Design Development and Evaluation of Nanostructured Lipid Carrier Loaded Emulgel of Voriconazole
Voriconazole is a second generation triazole derived from fluconazole. Voriconazole is used for the treatment of various fungal infections. Though it has excellent antifungal activity, there are several side effects associated with it. In order to overcome these limitations, nanostructures may be an…
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