Pharmaceutical tableting continues to be a vital step in manufacturing oral solid dosage forms. Even with progress in formulation science...

FROM CHALLENGE TO TRIUMPH Effervescent tablets pose unique formulation challenges — balancing tablet strength, dissolution, and appearance while managing large...

Introduction Roller compaction/dry granulation (RC/DG) is a key process in pharmaceutical manufacturing as it improves powder flowability, density, and segregation...

Abstract Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this...

Abstract The commercial implementation of continuous granulation requires an intelligent control framework compliant with Quality by Design (QbD) principles. To...

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...

Abstract Background/Objectives: Tablet development requires simultaneous optimization of multiple quality attributes under limited experimental budgets, yet formulation–property relationships are highly nonlinear...

Abstract This work evaluated the influence of oil type (sunflower vs. fish oil) and hydroxypropyl methylcellulose (HPMC) concentration on the...

Abstract Background/Objectives: Gastro-resistant multiparticulate systems are designed to protect drugs in acidic environments and to ensure intestinal release. In practice,...