Oleochemicals

Abstract Bigel, formed by high-speed shearing of hydrogel and oleogel, is suited to deliver both lipophilic and hydrophilic active compounds. patchouli oil and paeoniflorin, despite their potential in treating ulcerative colitis, face challenges due to patchouli oil’s poor aqueous solubility and…
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Abstract Given the recurrent waves of COVID-19 and the emergence of new viral infections, optimizing the potential of remdesivir as an antiviral agent is critical. While several reviews have explored the efficacy of remdesivir, few have comprehensively addressed its challenges, such as the…
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Abstract The main purpose of this study was to design and develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) for the oral administration of benidipine (BD) and telmisartan (TEL) using the adsorption method with eucalyptus oil, Transcutol P, and Kolliphor EL via the Box–Behnken…
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Abstract Background: Alopecia areata is an autoimmune disorder that causes hair loss in clumps about the size and shape of a quarter. The estimated prevalence of the disorder is approximately 1 in 1000 people, with a lifetime risk of approximately 2 percent. One of the systemic therapies for…
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Abstract Aims A new self-nanoemulsifying drug delivery system (SNEDDS) was developed for erlotinib (Ert) oral delivery. Highlights A pseudo-ternary phase diagram for olive oil, Tween 80 and PEG 600 was constructed. A SNEDDS composed of 10% olive oil, 20% Tween 80 and 70% (V)…
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Abstract This study developed a solid self-nanoemulsifying drug delivery system (S-SNEDDS) to improve the oral bioavailability of poorly soluble carvedilol using mesoporous silica nanoparticles (MSNs). The liquid self-nanoemulsifying drug delivery system (L-SNEDDS) consisted of carvedilol, Peceol,…
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Abstract Cutaneous fungal infections pose a significant health challenge, particularly in deeper skin layers where topical treatments are ineffective. Amphotericin B (AmB) is the gold standard for treating fungal infections, but its poor solubility limits its transdermal delivery. In this work, AmB…
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Abstract Background/Objectives: Interest in 3D printing oral thin films (OTFs) has increased substantially. The challenge of 3D printing is film printability, which is strongly affected by the rheological properties of the ink and having suitable mechanical properties. This research assesses the…
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Abstract Nanocapsules with core–shell structures hold significant potential across diverse applications. Biomimetic templating offers a benign approach for synthesizing inorganic nanostructures using biomolecules, leveraging amino acid sequences from natural sources and combinatorial biology in a…
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Abstract Salbutamol sulphate (SS) is a widely prescribed β2 agonist for different respiratory disorders. However, its short plasma half-life and poor oral bioavailability strongly limit its compliance. This study targeted formulating SS in nanostructured lipid carriers (SS-NLCs) embedded in a…
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