Disintegrants and superdisintegrant excipients are essential components used in the pharmaceutical industry to enhance the dissolution and bioavailability of active pharmaceutical ingredients (APIs). These excipients facilitate the disintegration and rapid breakup of tablets or capsules, which ultimately increases their rate of absorption in the body.
Pharma Excipients
Disintegrant / Superdisintergrant
Comparative analysis of tablet dissolution behavior: Batch vs. Continuous direct compression
Abstract
Continuous manufacturing offers advantages over traditional batch methods, including agility, efficiency, and sustainability. However, transitioning to continuous manufacturing in process development is challenging due to the need for early adoption of industrial-scale equipment.…
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Design of Experiments (DOE) – An essential tool to better understand tablet formulations
This paper covers a brief overview of the steps for pharmaceutical product development under the quality by design (QbD) framework; introduces design of experiments (DoE) applied to formulation of tablets and gives an example of how to design piroxicam amorphous solid dispersions (ASD) tablets using…
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Accelerated Medicines Development using a Digital Formulator and a Self-Driving Tableting…
Abstract
Pharmaceutical tablet formulation and process development, traditionally a complex and multi-dimensional decision-making process, necessitates extensive experimentation and resources, often resulting in suboptimal solutions. This study presents an integrated platform for tablet formulation…
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Compaction Characterisation of Piroxicam Amorphous Solid Dispersions Formulations
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Amorphous solid dispersions (ASDs) have been widely used to improve the bioavailability of poorly water-soluble drugs . They are comprised of high molar mass polymer carriers that stabilise the active pharmaceutical ingredients (APIs) in their amorphous state.…
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Formulation and Evaluation of Orodispersible Tablet of Piroxicam by using Natural Polymers
ABSTRACT:
Piroxicam is an oxicam class of NSAID which is a drug of choice in the treatment of severe pains occurs in chronic diseases like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and many more severe conditions. The solid dispersion method with piroxicam were prepared by…
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The Feasibility of the Repeated Administration of Acetylsalicylic Acid Mini-Tablets to Children with…
Background/Objectives: Mini-tablets are a novel pediatric dosage form designed to mask drug taste and facilitate easier administration. This study aimed to assess the feasibility and acceptability of uncoated acetylsalicylic acid (ASA) mini-tablets in Japanese children with Kawasaki disease (KD)…
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Gangwal Healthcare – A solutions provider for Complex, Innovative & Cutting-edge…
Powered By Innovation, Driving Health, Wellness & Healing
The building of a “best in class” solutions provider starts with understanding the complexities of a customer’s need and identifying gaps. New technologies and Drug Delivery Systems are studied and appropriate excipients or raw-materials…
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3D Printing of Tailored Veterinary Dual-Release Tablets: A Semi- Solid Extrusion Approach for…
Abstract
Metoclopramide (MCP) is frequently used to control nausea and vomiting in animals, but its short half-life requires it to be administered thrice daily. In addition, commercial veterinary MCP formulations are currently lacking. As a result,
veterinary practitioners often resort to…
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Orally disintegrating films based on pullulan and HPMC with carbopol-coated mucoadhesive…
Abstract
Dual-pattern drug release systems are a new type of drug delivery system designed to achieve both immediate and sustained drug release. This study developed a dual-pattern system by combining orally disintegrating films (ODFs) with mucoadhesive nanoparticles (NPs). The NPs were made from…
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Sallyso – Croscarmellose Sodium (CCS) by GANGWAL Healthcare
GANGWAL Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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