Disintegrant / Superdisintergrant

Introduction Chewable tablets represent an important patient-centric dosage form, particularly for pediatric, geriatric, and dysphagic populations where ease of administration...

Abstract Here, we report dissolution of aprepitant from three phospholipid-based amorphous solid dispersions (ASDs), namely binary ASDs containing drug and...

Abstract Successful development of direct-compression formulations can be hindered by poor compactibility of active pharmaceutical ingredients active pharmaceutical ingredients (APIs),...

Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...

Abstract Orodispersible tablet is a patient-friendly alternative for delivering the drug to patients having problems with swallowing and sensitive to...

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent...

See the latest edition of the Fuji Chemical Technical Newsletter: THE POLYMORPHISM CHALLENGE IN BILASTINE FORMULATION Bilastine is a second-generation,...

Abstract Background: ODT acetaminophen tablets are an alternative drug therapy for patients who have difficulty in swallowing tablets or capsules....

Abstract Orally disintegrating tablets (ODTs) are a solid oral dosage form designed to rapidly disintegrate in the mouth without the...