Disintegrant / Superdisintergrant

Abstract The layering of active pharmaceutical ingredient (API) suspension on inert carriers through fluid bed granulation has been tackled in...

Abstract Background This study aimed to identify suitable excipients for the development of vitamin C orally disintegrating tablets (ODTs) using...

Abstract Background Fast-disintegrating tablets (FDTs) are widely used oral dosage forms in which disintegration time is a critical quality attribute...

Abstract Background/Objectives: Tablet development requires simultaneous optimization of multiple quality attributes under limited experimental budgets, yet formulation–property relationships are highly nonlinear...

Introduction Chewable tablets represent an important patient-centric dosage form, particularly for pediatric, geriatric, and dysphagic populations where ease of administration...

Abstract Here, we report dissolution of aprepitant from three phospholipid-based amorphous solid dispersions (ASDs), namely binary ASDs containing drug and...

Abstract Successful development of direct-compression formulations can be hindered by poor compactibility of active pharmaceutical ingredients active pharmaceutical ingredients (APIs),...

Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...

Abstract Orodispersible tablet is a patient-friendly alternative for delivering the drug to patients having problems with swallowing and sensitive to...

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...