Sweeteners

Abstract The administration of medications to children has been a challenge for parents and caregivers for generations. Pharmaceutical companies have often overcome the difficulties of weight-based dosing and the ­inability of most young children to swallow solid dosage forms by creating oral…
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Abstract In the development of drugs misuse and addiction, references are often made to the study of the API (active principle ingredient) as the main cause, which is certainly true, but there is a tendency to overlook the possible role of certain excipients which may be involved in the…
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Abstract Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic drug delivery. This review examines various aspects of ODFs and their potential as a drug delivery…
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The objective of this work was to formulate zingiberine as medicated chewing gum for improving its bioavailability. The objective was achieved by isolating zingiberine form ginger oil and formulating chewing gum using zein as the gum base by melting method. The formulation of ZCGs was achieved using…
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Abstract The oral dissolving tablets is defined as one, which has drug in it and when placed on tongue dissolves completely within a limited span of time, without additional requirement of water. Drug is released, dispersed in the saliva and swallowed and subsequently absorbed in the…
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Pharmaceutical industry is constantly focused on researching patient-centered dosage forms that can maximize the therapeutic potential of an active pharmaceutical ingredient, as for example orodispersible form. The main advantage of orodispersible dosage forms is that they are suitable for patients…
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ABSTRACT Introduction Increasing attention is being afforded to understanding the bidirectional relationships that exist between oral medications and the gut microbiota, in an attempt to optimize pharmacokinetic performance and mitigate unwanted side effects. While a wealth of research has…
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Abstract Objectives This review aims at gleaning the currently available research reports that relate to 3D printlets for paediatric patients, and especially the excipients used to produce various colours, flavours, shapes and sizes. Methods A thorough literature review on paediatric 3D printed…
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Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and geriatric patients. Oral lyophilizates are solid forms, intended either to be placed in the mouth or to be dispersed (or dissolved) in water before administration. The correct…
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Speed. Precision. Patient-centricity. Roquette´s PEARLITOL® 200 GT granulated mannitol is here to revolutionize direct compression. Realize the potential of novel drug formats with smaller, harder tablets produced at unprecedented speeds – without compromising on quality. PEARLITOL® 200 GT…
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