Microcrystalline Cellulose

Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...

Abstract Tablet mechanical strength is governed by both the intrinsic mechanical properties of the constituent materials and the applied compaction...

Introduction Formulations comprising microcrystalline cellulose (MCC) are often used in wet granulation processes. In high shear wet granulation, MCC as...

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...

Introduction The future of pharmaceutical manufacturing industry is certainly linked with continuous manufacturing processes. Replacing the common batch procedures permits...

Abstract Background/Objectives: Canagliflozin (CFZ) is the first sodium glucose co-transporter 2 (SGLT-2) inhibitor and is characterized by poor water solubility...

Abstract In recent years, the environmental assessment and optimization of pharmaceutical dosage forms have received increasing attention. Consequently, interest in...

Introduction to Enzyme‑cleavable Methadone Prodrugs Enzyme‑cleavable methadone prodrugs represent a novel class of pharmacological agents designed to provide controlled release...

Abstract Powder flow is a constant concern in the production of solid dosage forms. Its concise and reliable determination and...

Abstract Background: ODT acetaminophen tablets are an alternative drug therapy for patients who have difficulty in swallowing tablets or capsules....