Organic Chemicals

Abstract Propolis is a widely studied natural raw material, the composition of which varies depending on the plant origin, harvest...

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

What are “enteric coated” capsules and why are they used? Enteric coating refers to a dosage form (e.g. capsule) of...

Biopharmaceutical excipients are the inactive substances added to biologic drug products to protect large, structurally fragile biomolecules, such as monoclonal...

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Capsugel® Enprotect® capsule enables enteric delivery without the need for a post-filling coating step. This helps protect your sensitive active...

Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....

Abstract Amorphous solid dispersions (ASDs) are widely used to enhance the solubility of poorly water-soluble drugs. Among commercial manufacturing approaches,...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...