Povidones

Abstract In pharmaceutical formulations, excipients are not inert additives but critical determinants of the solid-state properties, dissolution performance, and oral...

Abstract Polymers offer a promising alternative to established lipid nanoparticles for therapeutic RNA delivery. Here, we introduce alkyl-chain-quaternized poly(vinylpyrrolidone-co-4-vinylpyridine) copolymers...

Abstract Low adherence to daily oral drug regimens is a significant obstacle in effectively managing chronic therapies like HIV treatment,...

Abstract Microneedles represent a novel transdermal drug delivery technology that relies on micron-sized needle structures. This approach effectively penetrates the...

Abstract Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble...

Abstract Objectives: Fixed-dose combination tablets containing sitagliptin hydrochloride (SG) and metformin hydrochloride (MF) are a mainstay in the clinical management...

Abstract Aim Efonidipine hydrochloride ethanolate (EHE), a BCS Class II calcium channel blocker, exhibits extremely poor aqueous solubility and undergoes...

Abstract Cataract progression is closely associated with oxidative stress and inflammatory activation, while effective non-surgical interventions remain limited. Aesculetin (AES)...

Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...

Abstract This study investigates how the particle size range (PSR) of the polymeric component in a powder mixture affects the...