Pharma Excipients
3D Printing
Advancing medication compounding: Use of a pharmaceutical 3D printer to auto-fill minoxidil capsules…
Abstract
Compounding medications in pharmacies is a common practice for patients with prescriptions that are not available commercially, but it is a laborious and error-prone task. The incorporation of emerging technologies to prepare personalised medication, such as 3D printing, has been delayed…
Read More...
Read More...
Revolutionizing Drug Delivery with Gattefosse Innovative Lipid-Based Excipients – Interview
Discover the interview given by Alexandre Gil, Gattefossé Group Director for Pharmaceuticals, in Pharma Industrial India. In this interview, he discussed the advantages of Gattefossé excipients, the personalized medicine trend, the current Gattefossé R&D focus areas and their ambition for the…
Read More...
Read More...
Impact of disintegrants on rheological properties and printability in SSE 3D printing of…
Abstract
This study investigates the effects of disintegrants sodium starch glycolate (SSG) and crospovidone (CP) on the printability, rheological properties, and disintegration time of agar and hydroxypropyl methylcellulose (HPMC)-based formulations designed for semi-solid extrusion. Printability…
Read More...
Read More...
Fundamentals and future trends of 3D printing in drug delivery
Fundamentals and future trends of 3D printing in drug delivery
See the new book, edited by Dimitrios A. Lamprou and Dimitrios G. Fatouros. This book provides an in-depth discussion on key factors affecting the printing process such as different printer technologies, materials selection,…
Read More...
Read More...
3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-Trypanosoma cruzi Studies
Abstract
Background/Objectives: Chagas disease is a neglected tropical disease caused by infection with the parasite Trypanosoma cruzi. Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may lead to erratic bioavailability. This…
Read More...
Read More...
4D printing of shape-memory polymer-based floating tablets via fused deposition modelling:…
Abstract
The integration of four-dimensional (4D) printing technology into pharmaceutical manufacturing has introduced a transformative approach to drug delivery systems, offering flexible alternatives to improve drug bioavailability. This study advanced the field by developing an innovative…
Read More...
Read More...
For the good of the patient: Silica & Silicates from Evonik in the pharmaceutical industry
Many challenges – one solution: Fumed silica as well as precipitated silica and silicates from Evonik are some of the most important and highly utilized pharmaceutical excipients. Whether you manufacture medicines for solid, semi-solid or liquid dosing, we support you at every stage of product…
Read More...
Read More...
Miscibility, phase behavior, and mechanical properties of copovidone/HPMC ASLF and…
Abstract
Currently, most amorphous solid dispersion (ASD) formulations contain a single polymer to stabilize an amorphous drug. However, a single polymer has a limited ability to form strong drug-polymer interactions, resulting in poor drug loading (<30 % w/w) and a high pill burden. This…
Read More...
Read More...
Janus Nanoparticles Loaded 3D Bio Printed Scaffold as a Dual Drug Delivery System
Abstract
Herein, a new type of controlled-release system is fabricated using polycaprolactone (PCL) and poly(lactic-co-glycolic acid) (PLGA) nanoparticles for the creation preparation study. They include doxorubicin (DOX), a standard chemical for chemotherapy, and curcumin, part of the plant…
Read More...
Read More...
Kollidon® SR: Formulation techniques and drug delivery applications
Abstract
Kollidon® SR is one of the recent versatile coprocessed excipients in the formulation of modified release dosage forms. It is prepared by co-spray drying from aqueous dispersions of polyvinylacetate and polyvinylpyrrolidone. This article gives a critical review of the physicochemical…
Read More...
Read More...