Pharma Excipients
Starch
The impact of diluents on the compaction, dissolution, and physical stability of amorphous solid…
Abstract
Amorphous solid dispersion (ASD) is an effective approach for enhancing the solubility, dissolution, and bioavailability of poorly water-soluble drugs. However, these metastable forms can transform into more thermodynamically stable, less soluble crystalline forms. Despite this…
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A review on natural biopolymers in external drug delivery systems for wound healing and atopic…
Abstract
Despite the advantages of topical administration in the treatment of skin diseases, current marketed preparations face the challenge of the skin's barrier effect, leading to low therapeutic effectiveness and undesirable side effects. Hence, in recent years the management of skin wounds,…
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Lamellar double hydroxides as pharmaceutical excipients: a compatibility study
Lamellar double hydroxides (LDH) are a class of inorganic materials widely used as pharmaceutical ingredients. However, their use as excipients and mainly as drug carriers lacks specific research in pharmaceutical technology, as there are no publications capable of defining the behavior of these…
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Meet Customer Demand with Plant-Based ADM Excipients and API
The trend toward products with plant-based ingredients continues to grow as a result of customer demand. ADM can help you with high quality, low toxicity ingredients that are cost-effective, bio-compatible and easily available.
In addition to providing high-quality APIs and excipients, ADM is…
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Biopolymer Packaging Materials in the Pharmaceutical Industry
Biopolymer packaging materials are gaining prominence in the pharmaceutical industry due to environmental concerns. Derived from renewable sources, these biopolymers offer biodegradability, biocompatibility, and non-toxicity, making them ideal for various pharmaceutical applications. In drug…
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A Comprehensive Review of Disintegrants: Backbone of disintegration
Abstract
Strong attractive bonding forces works among the particles of solid dosage forms such as mechanical, solid and intermolecular and bioavailability of solid dosage form is preferentially dependent on in vivo disintegration then dissolution. This review is focused for disintegrating agents,…
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Quantitative analysis of wet kneading states by a novel compression test
Kneading is a process that mixes powders with liquid to produce homogeneous wet powders, with the process of kneading significantly affecting the quality and productivity of the final product. However, most kneading operations are controlled by the empirical judgment of experts. This study focused…
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Addiction to Psychoactive Prescription Drugs: Can the Excipients of the Formulations Play a Role?
Abstract
In the development of drugs misuse and addiction, references are often made to the study of the API (active principle ingredient) as the main cause, which is certainly true, but there is a tendency to overlook the possible role of certain excipients which may be involved in the…
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Development, Physicochemical Characteristics and Pharmacokinetics of a New Sustained-Release Bilayer…
Abstract
Background and Objective
There are some potential concerns about the currently marketed solid oral dosage forms of tramadol, including decreased adherence to immediate-release (IR) formulations due to the high number of doses taken each day and the slow rise in the blood tramadol…
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Orodispersible Films: Current Innovations and Emerging Trends
Abstract
Orodispersible films (ODFs) are thin, mechanically strong, and flexible polymeric films that are designed to dissolve or disintegrate rapidly in the oral cavity for local and/or systemic drug delivery. This review examines various aspects of ODFs and their potential as a drug delivery…
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