Pharma Excipients
Starch
3D-printed chewable gummy tablets: A new tool for oral amoxicillin administration in paediatric…
Abstract
Amoxicillin is one of the most prescribed antibiotics in the paediatric population. Currently available formulations (i.e., suspensions and tablets) suffer from limited acceptability often responsible for the therapeutic failure. In the present study it is proposed an innovative…
Read More...
Read More...
A porridge-like hydrogel promoted the oral bioavailability of veterinary medicines
Abstract
The administration of veterinary medicines via drinking water or feed ingredients is a widely adopted method in intensive livestock and poultry farming due to its convenience and cost-effectiveness. Among these drugs, antimicrobials are extensively used, with over 70% of global…
Read More...
Read More...
Clinical implementation of a paediatric 3D-printed combination of Sulfamethoxazole and Trimethoprim
Abstract
Adherence to treatment is one of the major challenges in chronic diseases. Inappropriate dosage forms or bad taste are the main factor for non-adherence, especially in paediatric patients. 3D printed medicines could be tailored to specific patients to make medicines more acceptable,…
Read More...
Read More...
Influence of material and process parameters on the correction factor Kp in roller compaction…
Abstract
It is widely believed that compaction simulators can replicate the uniaxial compression process of a roller compactor. The correction factor (Kp) is a parameter used to adjust a mathematical model for compaction simulation to obtain the same product relative density, therefore accounting…
Read More...
Read More...
Presence of gluten and soy derived excipients in medicinal products and their implications on…
Abstract
Gluten and soy allergies are significant health concerns, particularly in individuals with celiac disease or soy sensitivity. While dietary sources of these allergens are well-studied, their presence in medicinal products remains under-explored. This study assessed the prevalence of gluten…
Read More...
Read More...
From Oral to Sublingual: A Redefined Avanafil Tablet with a Breakthrough in Bioavailability and…
Abstract
Introduction
Avanafil (AVA) is a very efficient phosphodiesterase type 5 inhibitor for the treatment of erectile dysfunction. However, it has limited bioavailability when taken orally and considerable first-pass metabolism. Enhancing its solubility and choosing an alternative delivery…
Read More...
Read More...
Veterinary soft chews using Gelucire® 50/13 and Precirol® ATO 5 – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
A proof of concept with wet extrusion
Introduction
Veterinary soft chews are gaining interest among oral dosage forms for companion animals as they provide good acceptance for the pet and are easy to administrate by the pet owner,…
Read More...
Read More...
Mixing efficiency of pharmaceutical powders in an intensive mixer with rotating mixing vessel
The mixing of ductile lubricant particles is known to have several negative effects on tablet properties, such as decreased hardness and delayed disintegration. This study investigated the usefulness of a mixing system using an intensive mixer with a rotating mixing vessel (EIRICH Intensive Mixer)…
Read More...
Read More...
Webinar Next-Gen Film Coatings: Merging Sustainability with Superior Performance
The pharmaceutical and nutraceutical industries have traditionally relied on Hydroxypropyl Methylcellulose (HPMC) and Polyvinyl Alcohol (PVA) as the standard polymers for immediate release coatings for solid oral dosage forms. These polymers are commonplace due to their robustness and…
Read More...
Read More...
The Feasibility of the Repeated Administration of Acetylsalicylic Acid Mini-Tablets to Children with…
Background/Objectives: Mini-tablets are a novel pediatric dosage form designed to mask drug taste and facilitate easier administration. This study aimed to assess the feasibility and acceptability of uncoated acetylsalicylic acid (ASA) mini-tablets in Japanese children with Kawasaki disease (KD)…
Read More...
Read More...