Pharma Excipients
Fatty Alcohols
Essential oils: a review on their salient biological activities and major delivery strategies
Essential oils are volatile, complex products of plants as secondary metabolites and include terpenes and their oxygenated derivatives, such as alcohols, aldehydes, esters, ketones, phenols and oxides. In recent years, out of 3000 essential oils obtained from plant origin only 300 essential oils…
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Prilling of API/fatty acid suspensions: processability and characterisation
Current study evaluated the processability and characteristics of prills made of an active pharmaceutical ingredient/fatty acid (API/FA) suspension instead of previously studied API/FA solutions to enlarge the application field of prilling.
Metformin hydrochloride (MET) and paracetamol (PAR) were…
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Gliding performance of solid oral dosage form film coatings using an artificial mucous layer
Oral drug delivery technology is mainly provided in the form of solid oral dosage forms (SODF) that have to be swallowed intact and move throughout the oro-esophageal system to release the drug content in the stomach or intestine. As there is growing evidence for an increasing prevalence of impaired…
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Current Developments in Excipient Science – Implication of Quantitative Selection of Each…
Implication of Quantitative Selection of Each Excipient in Product Development
Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
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Pharmaceutical preformulation studies and paediatric oral formulations of sodium dichloroacetate
The purpose of this study was to develop liquid and solid paediatric formulations of sodium dichloroacetate (DCA) for the treatment of congenital lactic acidosis (CLA). In this work preformulation studies on the active molecule were performed to identify those physico-chemical properties of the drug…
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