Polyethylene Glycol (PEG)

Abstract This study explores the development of a self-nanoemulsifying drug delivery system (SNEDDS) to enhance the biopharmaceutical profile of lornoxicam,...

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while...

Article by David Tisi, Senopsys LLC: The principle of dual sourcing excipients is well established in pharmaceutical development, and its importance...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...

Abstract Biomacromolecules including peptides, proteins, antibodies, and gene medicines, comprise important classes of therapeutics in treating disease. A drawback of...

Abstract Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by...

CARBOWAX™ SENTRY™ Polyethylene Glycols (PEGs), CARBOWAX™ SENTRY™ Methoxypolyethylene Glycols (MPEGs), and VERSENE™ NA Edetate Disodium are among the most versatile...

Abstract Purpose Conventional chemotherapy is limited by premature drug leakage, systemic toxicity, and inefficient intracellular co-delivery, leading to reduced therapeutic...

Abstract Building on growing evidence that ionizable lipids improve RNA delivery, in this work, we developed ionizable lipid/poly(lactic-co-glycolic acid) hybrid...