Lubricant excipients are substances that are added to tablet formulations to aid in the tableting process and to improve the flow of powders during the manufacturing of tablets. These excipients reduce friction and prevent the sticking of the tablet material to the surface of the die and punches, allowing for smoother tablet production and reducing the wear and tear on the tableting equipment.
Pharma Excipients
Lubricant
BASF Lubricants for Oral Applications
High-quality lubricants for solid oral dosage forms
BASF's Lubricant Portfolio includes hydrophilic and hydrophobic GMP-grade excipients to ensure high performance and robust tableting operations. Choose from a range of tailored solutions for batch or continuous manufacturing.
What is a…
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Unveiling tablet structural changes: A micro computed tomography analysis of aqueous coating effects
Abstract
Tablet coating with aqueous solvents represents a well-established environmentally sustainable alternative to coatings based on organic solvents. However, this practice requires a careful evaluation of potential quality issues, such as increased porosity and crack formation stemming from…
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Mastering the Softgel Encapsulation Process: A Deep Dive into Precision Manufacturing
Softgel capsules are a cornerstone of modern pharmaceutical and nutraceutical industries, offering consumers a seamless, easy-to-swallow solution that enhances bioavailability and ensures precise dosing. This article will examine the intricate processes involved in softgel encapsulation,…
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Facilitate Precise Direct Tableting Operations by Producing Uniform, Hard Tablets That Meet…
Introduction
Direct tableting Lactose is widely used as an excipient in tableting applications due to inert chemical properties, as well as its superior compression and compaction characteristics. Direct tableting is widely used in the pharmaceutical industry due to it’s simplicity versus other…
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Simultaneous prediction of the API concentration and mass gain of film coated tablets using…
Abstract
This study investigates the simultaneous prediction of active pharmaceutical ingredient (API) concentration and mass gain in film-coated tablets using Partial Least Squares (PLS) regression combined with three data fusion (DF) techniques: Low-Level (LLDF), Mid-Level (MLDF), and…
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Influence of multiple compression phases during tableting of spray dried Saccharomyces cerevisiae on…
Abstract
The viability of probiotic microorganisms is essential for their health-promoting effects and must be preserved in the best possible way during the production of the final dosage form, such as tablets. This applies to both drying and tableting. Saccharomyces cerevisiae is spray-dried…
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Magnesium Stearate Fatty Acid Composition, Lubrication Performance and Tablet Properties
Abstract
Magnesium stearate (MgSt) is a common tablet lubricant. As variations in MgSt properties are known to influence tablet attributes, the impact of MgSt fatty acid composition, particularly the significance of the stearate and palmitate contents, and its effects on tablet properties…
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Design and optimization of stirrer and mixer design for the correct mixing of pharmaceutical powders…
Abstract
Mixing of granular materials is an important process for pharmaceutical industries. In this study, a quantifiable calculation method was suggested to determine the final mixing degree of the mixture. Based on that, the effect of the stirrer design, rotational speed, powder density,…
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The Role of Excipients in Pharmaceutical Powder-to-Tablet Continuous Manufacturing
Abstract
The pharmaceutical industry is continuously looking for strategies and solutions that can improve quality and efficiency of manufacturing processes. As a result, there has been a significant shift towards continuous manufacturing (CM). Traditionally, tablets have been produced by batch…
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Optimizing Tablet Formulation through Integrated Use of Digital Formulation Tools and Compaction…
This poster was presented at the AAPS 2024 by BASF, KORSCH and MEDELPHARM:
PURPOSE
The aim of this study was to optimize the formulation and production process of pharmaceutical tablets using an integrated approach involving algorithm-based formulation tool (ZoomLab®) and a compaction simulator…
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