Taste Masking of Drug Layered Pellets with the Kollicoat® Smartseal 100P
Taste-masking has proven to be a useful technique to improve patient compliance of oral dosages having bitter actives, especially for pediatric and geriatric products. Kollicoat® Smartseal 100P, a spray dried powder of methyl methacrylate-diethylaminoethyl methacrylate copolymer is an excellent coating polymer for taste masking as it is insoluble…
News on Pharma Excipients
Vacuum Compression Molding as a Screening Tool to Investigate Carrier Suitability for Hot-Melt Extrusion Formulations
Hot-melt extrusion (HME) is the most preferred and effective method for manufacturing amorphous solid dispersions at production scale, but it consumes large amounts of samples when used for formulation development. Herein, we show a novel approach to screen the polymers by overcoming the…
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