Pharma Excipients

NEWS ON PHARMA EXCIPIENTS

Crospovidone

Optimization of Hot-Melt Granulation for High-Dose Tinidazole Tablets: Effects on Dissolution Enhancement and Taste Masking

27. June 2026

Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while balancing dissolution enhancement and bitterness control. Methods Polyethylene glycol (PEG)...

BASF

High Drug-loading Simvastatin Formulation: Hot Melt Extrusion and Self-microemulsifying Drug Delivery System

Abstract Purpose Simvastatin (SIM) is a widely prescribed lipid-lowering agent; however, its clinical efficacy is hindered by poor aqueous solubility...

27. June 2026

Ashland

Design of immediate release combination preparation containing alkalizer and lansoprazole for mechanistic understanding of enhanced gastric stability, pharmacokinetics, and intragastric pH variability in healthy human subjects

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

26. June 2026

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