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Optimization of Hot-Melt Granulation for High-Dose Tinidazole Tablets: Effects on Dissolution Enhancement and Taste Masking
Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while...
High Drug-loading Simvastatin Formulation: Hot Melt Extrusion and Self-microemulsifying Drug Delivery System
Abstract Purpose Simvastatin (SIM) is a widely prescribed lipid-lowering agent; however, its clinical efficacy is hindered by poor aqueous solubility...
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