Pharma Excipients

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Gattefossé

DoE-guided comparison of SNEDDS, solid dispersion, and polymeric nanoparticles for enhancing apparent epithelial transport and oral exposure of sorafenib

14. September 2026

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor oral bioavailability. Although sorafenib is generally considered dissolution-limited, its oral...

BASF

Development and Characterization of Solid Dispersions of Azithromycin Using Poloxamer 407 and Syloid 244FP®

Abstract Purpose Azithromycin, a macrolide antibiotic, exhibits dissolution-limited oral absorption due to its poor solubility, and that affects its therapeutic...

14. September 2026

3D Printing

Mechanistic Comparison of Semi-Solid Extrusion 3D-Printed Printlets and Hot-Moulded Tablets: Linking Polymer–API Interactions, Microstructure, and Dissolution of Plant-Based Formulations

Abstract Background: Three-dimensional printing (3DP) is rapidly advancing personalised medicine, yet systematic performance comparison with conventional manufacturing remains limited, particularly...

13. September 2026

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