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NEWS ON PHARMA EXCIPIENTS
Ocular topical aesculetin delivery via VA64/TPGS co-assembled micelles for redox-inflammatory modulation in selenite-induced cataract
Abstract Cataract progression is closely associated with oxidative stress and inflammatory activation, while effective non-surgical interventions remain limited. Aesculetin (AES)...
Mechanistic evaluation of sulfobutylether-β-cyclodextrin complexation as a formulation strategy to enhance solubility and oral exposure of BCS Class II compounds
Abstract Poor aqueous solubility is a major cause of solubility-limited absorption and misleading pharmacokinetic outcomes during early oral drug discovery....
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