Petrochemicals

The effect of binder types on the granule properties and tablet quality for high shear wet granulation and tableting (HSWG-T) was studied. Furthermore, attribute correlation was established by multivariate models based on a systematical study of the binder’s properties, wetting mass’s physical…
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Abstract Mesoporous silica carriers are known to improve the solubility and bioavailability of poorly soluble Class II drugs. However, most mesoporous silica carriers available in the market have relatively low drug loading capacities. Therefore, it is essential to select the appropriate mesoporous…
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Abstract The phase inversion temperature method is one of the formulation processes to elaborate nanomedicine based on lipid nanoparticles. This process was used in numerous studies in literature, changing the nature of the ingredients to ensure good encapsulation efficiencies of various drugs.…
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Abstract The flavonoid hesperidin is a crucial, biologically active substance of great interest because of its polypharmacological properties and high safety profile. However, its widespread use of this bioflavonoid in remedies for the treatment and prevention of various diseases is limited by its…
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Abstract Metoclopramide (MCP) is frequently used to control nausea and vomiting in animals, but its short half-life requires it to be administered thrice daily. In addition, commercial veterinary MCP formulations are currently lacking. As a result, veterinary practitioners often resort to…
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Abstract Aims A new self-nanoemulsifying drug delivery system (SNEDDS) was developed for erlotinib (Ert) oral delivery. Highlights A pseudo-ternary phase diagram for olive oil, Tween 80 and PEG 600 was constructed. A SNEDDS composed of 10% olive oil, 20% Tween 80 and 70% (V)…
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Introduction: Punch sticking is a common phenomenon in tablet manufacturing, often leading to tablet defects and compromise product quality. A thorough understanding of the sticking mechanism is essential to optimize the tablet production process. The aim of this study was to investigate the…
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Abstract A tunable modular design (TMD) as a new approach was proposed to tailor the dose and drug release profile of poorly water-soluble drugs from hydroxypropyl methylcellulose (HPMC)-based solid foams by combining two manufacturing principles: (1) freeze-drying aqueous HPMC-based gels to…
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Abstract Oral drug administration is the preferred route for pharmaceuticals, accounting for ~90% of the global pharmaceutical market due to its convenience and cost-effectiveness. This study provides a comprehensive scientific and technological analysis of the latest advances in oral dosage forms…
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Abstract Inkjet printing is emerging as a valuable tool for personalised medicine, offering precision and flexibility in pharmaceutical development. Efforts have been made to modify commercial desktop printers; however, the growing demand for decentralized and on-demand pharmaceutical production…
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