Petrochemicals

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while...

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....

Article by David Tisi, Senopsys LLC: The principle of dual sourcing excipients is well established in pharmaceutical development, and its importance...

Abstract Amorphous solid dispersions (ASDs) are widely used to enhance the solubility of poorly water-soluble drugs. Among commercial manufacturing approaches,...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...

Abstract The physical stability of salbutamol amorphous solid dispersion (ASD) pharmaceutical tablets, manufactured via a novel strategy employing liquid drug...

Abstract A comprehensive understanding of drugs and excipients is crucial for developing a stable pharmaceutical formulation. Pre-formulation studies include the...