Petrochemicals

Abstract Laser powder bed fusion (LPBF) is a promising additive manufacturing technology for producing personalized pharmaceutical dosage forms at industrial...

Abstract Lipid nanoparticles (LNPs) administered parenterally often show poor localization to multiple tissue types, including the pancreas and gastrointestinal (GI)...

Abstract The present study aimed to develop and optimize a shikonin-loaded mucoadhesive microemulsion for intranasal delivery with the objective of...

Abstract Objective CACN136 is a novel curcumin analogue with antidepressant potential, but its poor aqueous solubility may restrict oral absorption....

Abstract In pharmaceutical formulations, excipients are not inert additives but critical determinants of the solid-state properties, dissolution performance, and oral...

Abstract Background/Objectives: Solid self-nanoemulsifying drug delivery systems (SNEDDS) prepared by adsorption onto porous carriers are widely used to improve the...

Abstract Polymers offer a promising alternative to established lipid nanoparticles for therapeutic RNA delivery. Here, we introduce alkyl-chain-quaternized poly(vinylpyrrolidone-co-4-vinylpyridine) copolymers...

Abstract Low adherence to daily oral drug regimens is a significant obstacle in effectively managing chronic therapies like HIV treatment,...

Abstract Microneedles represent a novel transdermal drug delivery technology that relies on micron-sized needle structures. This approach effectively penetrates the...

Abstract Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble...