Pharma Excipients
Flavour / Flavor
Taste Masking of Orodispersible Films: A Case Study in Palatability Optimization
It's all about the taste when David Tisi from Senopsys writes an article and we are happy to share his view on "Taste Masking of Orodispesible Films" with you in this article.
Orodispersible films (ODFs) are strips of water-soluble polymer matrices which contain an active ingredient that dissolves…
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Veterinary soft chews using Gelucire® 50/13 and Precirol® ATO 5 – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
A proof of concept with wet extrusion
Introduction
Veterinary soft chews are gaining interest among oral dosage forms for companion animals as they provide good acceptance for the pet and are easy to administrate by the pet owner,…
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Complete solutions for pharmaceutical and nutraceutical coatings by Roquette
Coatings play a crucial role in enhancing patient compliance and adherence to prescription drugs in the pharmaceutical industry, as well as improving consumer experience for nutraceuticals and over-the-counter (OTC) markets.
Film coating solutions
From masking unpleasant tastes and odors to…
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Formulation and Evaluation Oral Dispersible Tablets of Vibegron
Abstract
In the present work, taste masking of Vibegron was carried out by using strong cation exchange resin tulsion 344. These taste-masked complexes were further formulated into the Oro dispersible tablet by the direct compression method using Ac-Di-Sol and Avicel as a super disintegrant.…
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Evaluation of azithromycin–resin suspension designed for taste-masking and sustained-release
Abstract
Purpose: To prepare azithromycin (AZI) sustained-release suspension containing AZI-coated microcapsules (AZI-CM) impregnated with AZI-drug resin complex (AZI-DRC), in order to mask the bitter taste of AZI and improve the oral compliance of patients.
Methods: The AZI-DRC was prepared…
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Development of a pediatric oral solution of ONC201 using nicotinamide to enhance solubility and…
Abstract
Diffuse intrinsic pontine glioma (DIPG) poses a significant treatment challenge in pediatric patients due to its aggressive nature and difficulty in crossing the blood–brain barrier with effective therapies. ONC201 (dordaviprone) shows promises in inducing apoptosis in cancer cells but…
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Taste Masking Challenge of 155 Active Pharmaceutical Ingredients
Abstract
Regulations in the US and EU require and incentivize the development of palatable, age-appropriate medicines for children. However, the taste masking challenge of new drug actives is generally unknown, making development of palatable drug products extremely difficult. To develop palatable…
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3D printed personalized therapies for pediatric patients affected by adrenal insufficiency
ABSTRACT
Background
Adrenal insufficiency is usually diagnosed in children who will need lifelong hydrocortisone therapy. However, medicines for pediatrics, in terms of dosage and acceptability, are currently unavailable.
Research design and methods
Semi-solid extrusion (SSE) 3D printing…
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Aroma and Flavor in Product Development: Characterization, Perception, and Application – Part…
Characterization, Perception, and Application
See the new book, edited by Rajnibhas Sukeaw Samakradhamrongthai. This guide provides essential insights into perception, formation, and development, enabling developers to enhance food items' organoleptic qualities and thereby provide consumers with an…
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Aroma and Flavor in Product Development: Characterization, Perception, and Application – Part…
Characterization, Perception, and Application
See the new book, edited by Rajnibhas Sukeaw Samakradhamrongthai. This guide provides essential insights into perception, formation, and development, enabling developers to enhance food items' organoleptic qualities and thereby provide consumers with an…
Read More...
Read More...