Nanotechnology

Abstract Therapeutic agents approved for the topical treatment of dermatological diseases have diverse physicochemical properties, but they are frequently poorly...

Abstract Aims The objective of the present study was to develop and characterize tamoxifen (TAM)-loaded TPGS-PLGA nanoparticles (NPs) for more...

Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) aggregation and limited treatment efficacy due to...

Abstract Nanospheres hold great promise for drug delivery but face challenges in achieving both high drug loading and sustained release....

Highlights PLGA/PBAE coordinates endosomal escape and timely mRNA release in APCs PLGA/PBAE enhances mRNA transfection in APCs and promotes immune...

Abstract The concurrent rise of autoimmune diseases, which affect nearly 10% of the global population, along with allergic conditions such as...

Abstract A d-α-Tocopheryl Polyethylene Glycol-1000 Succinate (TPGS)-functionalized nanoparticle formulation was developed for the co-delivery of Paclitaxel (PTX) and Gefitinib (GEF)...

Abstract Small interfering RNA (siRNA)-loaded lipid nanoparticles (LNPs) are a promising modality for gene silencing therapies. Pulmonary delivery offers an...

Abstract The present study aimed to design, optimize, and evaluate enteric-coated nanocarriers to enhance the oral bioavailability of Rifaximin, a...

Abstract Endometriosis (EM) is a gynaecological disorder for which drug combinations such as atorvastatin (ATV) and silybin (SB) hold therapeutic...