Nanotechnology

Abstract Psoriasis is a chronic, autoimmune-driven inflammatory skin disorder characterized by red, scaly lesions, keratinocyte hyperproliferation, and infiltration of inflammatory...

Abstract Pediatric maintenance therapy for acute lymphoblastic leukemia requires prolonged daily administration of 6-mercaptopurine (6-MP), a drug characterized by a...

Abstract Drug delivery using self-assembling drug-excipient nanoparticles offers a scalable strategy to improve the solubility, bioavailability, and biodistribution of poorly...

Abstract Polymers offer a promising alternative to established lipid nanoparticles for therapeutic RNA delivery. Here, we introduce alkyl-chain-quaternized poly(vinylpyrrolidone-co-4-vinylpyridine) copolymers...

Abstract IBD (inflammatory bowel disease and colorectal cancer (CRC) are significant health challenges worldwide that are projected to rise substantially...

Abstract Diabetes mellitus currently affects an estimated 635 million individuals worldwide. Insulin therapy remains the primary treatment option for patients...

Abstract Hesperetin (HSP), a naturally occurring citrus flavanone with diverse antioxidant, anti-inflammatory, and pharmacological activities, has attracted considerable attention as...

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor...

Abstract Triple negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes that is characterized by the...

Abstract Poor aqueous solubility limits the in vitro dissolution performance of many drugs, among them curcumin which is a bioactive...