Taste Masking

About our company The Gattefossé Group is a community of employees, all driven by a dual mission: the performance of its products and the personalized support to its customers. Gattefossé develops, manufactures and sells cosmetic ingredients and pharmaceutical excipients of natural origin for…
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Abstract Interest in minitablets (MTs) has grown exponentially over the last 20 years and especially the last decade, as evidenced by the number of publications cited in Scopus and PubMed. MTs offer significant opportunities for personalized medicine, dose titration and flexible dosing, taste…
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Abstract The administration of medications to children has been a challenge for parents and caregivers for generations. Pharmaceutical companies have often overcome the difficulties of weight-based dosing and the ­inability of most young children to swallow solid dosage forms by creating oral…
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The field of oral drug delivery has witnessed significant advancements, with a focus on developing innovative formulations to address challenges associated with traditional dosage forms, especially for patients with difficulties in swallowing. Fast Dissolving Tablets (FDTs) have emerged as a…
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Abstract Orally disintegrating granules (ODGs) are a pharmaceutical form commonly used for the administration of NSAIDs because of their easy assumption and fast dispersion. The development of ODGs is not easy for drugs like dexketoprofen trometamol (DXKT), which have a bitter and burning taste. In…
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Functional film coatings are a topic which considers many formulators. Therefore we gladly share this interesting overview by BIOGRUND. Definition of “Functional Film Coating”: A functional film coating has an influence on the drug release and is used to modify the release of the active…
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Abstract Introduction and purpose The unpleasant extremely bitter taste of the orally administered broad-spectrum antibiotic azithromycin decreases patient compliance, especially in pediatrics. This issue can be overcome by decreasing drug interaction with the tasting buds using insoluble…
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Abstract Carvedilol (CARV) is a blocker of α- and β- adrenergic receptors, used as an “off-label” treatment for cardiovascular diseases in pediatrics. Currently, there is no marketed pediatric-appropriate CARV liquid formulation, so its development is necessary. Palatability (appreciation of smell,…
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ABSTRACT A novel drug delivery system plays a pivotal role in enhancing patient adherence to medication regimens. Among these innovative approaches, fast dissolving tablets (FDT’s) stand out as a particularly promising option. FDT’s offer a range of benefits, including precise dosing, ease of…
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In a 2003 survey conducted by the American Association of Pediatrics, unpleasant taste was identified as the most significant barrier to completing treatment in pediatrics. Drug taste masking is extremely relevant to improve patient convenience and compliance. It's currently a relevant…
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