Taste Masking

It is widely recognized that many Active Pharmaceutical Ingredients (APIs) are bitter, some extremely so. But bitterness is not the only challenge in creating palatable, patient-accepted drug products. If not bitter, what are other common aversive sensory attributes? To answer this question, data…
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Oral pediatric formulations are either ready-to-use or require manipulation, and multi-use or single-use. Strong encouragement for preservative-free pediatric formulations has resulted in fewer multi-use solutions or suspensions in favor of single-use solid oral dosage forms. This updated review…
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It is widely recognized that many Active Pharmaceutical Ingredients (APIs) are bitter, some extremely so. But bitterness is not the only challenge in creating palatable, patient-accepted drug products. If not bitter, what are other common aversive sensory attributes? To answer this question, data…
Read More...

The aim of this research was to use inkjet printing technology in formulation of personalized medicine. Thus in this research, an attempt was made to print OTF by TIJ printing. A placebo solution comprising of different polymers and polymer concentrations was used for TIJ printing on A4 paper. The…
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Prolonged drug release provided by multiple-unit dosage forms is highly beneficial to enhance the compliance and safety of the pharmacotherapy even for patients with swallowing deficiencies. To facilitate the intake for these patients, multiple-unit tablets and capsules have to be crushed or opened.…
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Alkindi® is a novel oral multi-particulate taste-masked formulation of hydrocortisone for use in children with the rare disease adrenal insufficiency. The objective of the present work was to study the biorelevant dissolution and compatibility properties of Alkindi® granules following…
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Lipid coating in a high shear blender without heating and complex spray mechanism was investigated as a simplified approach to hot melt coating in a fluid bed device. Potassium chloride was coated with 20% glyceryl distearate using both processes. Microscopic images revealed that the drug surface…
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In this video Chris Moreton gives an interesting insight on pharmaceutical excipients. 
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Oral modied-release multiparticulate dosage forms, which are also referred to as oral multiple-unit particulate systems, are becoming increasingly popular for oral drug delivery applications. The compaction of polymer-coated multiparticulates into tablets to produce a sustained-release dosage form…
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What is an orally disintegrating dosage form? An orally disintegrating tablet is a novel formulation that dissolves in the saliva within a few seconds and without requiring of drinking additional water. This dosage form is a powerful way to deliver active drugs ingredients because it has many…
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