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Taste Masking
Taste Masking of Primaquine Phosphate: A Comparative Evaluation of Three Taste Masking Agents
Abstract
The work involved taste masking of primaquine phosphate (PMQ), an intensely bitter drug used in the prevention and treatment of relapses of malarial infections caused by Plasmodium vivax and ovale. Drug and cation exchange resins viz, AmberLite™ IRP 64, 69, and 88 (IER 64, IER69, and…
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Taste Masking of Orodispersible Films: A Case Study in Palatability Optimization
It's all about the taste when David Tisi from Senopsys writes an article and we are happy to share his view on "Taste Masking of Orodispesible Films" with you in this article.
Orodispersible films (ODFs) are strips of water-soluble polymer matrices which contain an active ingredient that dissolves…
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Evaluating dosing accuracy and galenic dispersion quality in Hospital-Based pediatric spironolactone…
Abstract
Compounded oral suspensions of spironolactone are commonly used in pediatric patients with heart conditions. However, due to its poor solubility in water, spironolactone suspensions may lead to sedimentation, compromising homogeneity and dose accuracy. This study aimed to assess dose…
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Poor-tasting pediatric medicines: part 2. Exploring caregiver and healthcare provider values and…
Abstract
Introduction: Improving the palatability of bitter-tasting medication for pediatric populations has long presented a challenge. Taste blockers are being researched as a potential solution; however, end-user perspectives and needs related to this concept have not been explored. The…
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Poor-tasting pediatric medicines: Part 1. A scoping review of their impact on patient acceptability,…
Abstract
Background: Many medicines for children taste bitter and unpleasant, presenting a significant barrier to effective pharmacotherapy. Anecdotally, this issue is widely recognized; however, empirical evidence on the consequences of unpalatable medicines remains scarce and fragmented. The…
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Veterinary soft chews using Gelucire® 50/13 and Precirol® ATO 5 – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
A proof of concept with wet extrusion
Introduction
Veterinary soft chews are gaining interest among oral dosage forms for companion animals as they provide good acceptance for the pet and are easy to administrate by the pet owner,…
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New product – Kleptose F 7% – BETA CYCLODEXTRIN
Roquette presents a new product:
KLEPTOSE® F 7% - EXP β-cyclodextrin for oral dosage forms contains less than 7% of water. It is well suited for dry processing techniques, such as direct compression, where its low water content benefits moisture-sensitive APIs and formulations (e.g., ODTs,…
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Taste-masked pellets of sodium warfarin prepared by hot melt extrusion – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
Introduction
Fig. 1. 20% drug-loaded particle microscopy before (A) and after (B) 360 minutes of thermal treatment, magnification (40x)
Warfarin, a coumarin derivative, is an indirect-acting anticoagulant and a vitamin K…
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The Feasibility of the Repeated Administration of Acetylsalicylic Acid Mini-Tablets to Children with…
Background/Objectives: Mini-tablets are a novel pediatric dosage form designed to mask drug taste and facilitate easier administration. This study aimed to assess the feasibility and acceptability of uncoated acetylsalicylic acid (ASA) mini-tablets in Japanese children with Kawasaki disease (KD)…
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DRUGCOAT – Excellence in Pharma Polymer by Vikram Thermo
Vikram Thermo (India) Limited, was established in the year 1984, near Ahmedabad, Gujarat for manufacturing Di Phenyl Oxide in the name of Vikram Enterprise Private Limited, a pioneer in the manufacturing of DPO. Later on company also entered into the business of developing pharma polymer products -…
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