Solubilizer

Abstract Sorafenib is an orally administered multikinase inhibitor whose clinical utility is limited by extremely low aqueous solubility and poor...

Abstract Despite various attempts at solubility enhancement and advances in formulation technologies, improving the bioavailability of poorly water-soluble compounds remains...

Formulation of poorly soluble APIs remains one of the most persistent challenges in modern pharmaceutical development. With a growing number...

Lipid-based excipients from IOI Oleo help to improve the bioavailability of poorly soluble active ingredients. The majority of new active...

Gattefossé is a leading supplier of functional excipients for veterinary industries worldwide, enabling to formulate any dosage form for any...

Abstract Amorphous solid dispersion (ASD) is a widely used formulation strategy for improving the apparent solubility and oral absorption of...

Abstract Transdermal drug delivery offers several advantages over conventional routes. However, its use is limited by the low permeability of...

A significant proportion of new drug candidates present limited aqueous solubility. This is a well-documented formulation challenge, particularly for oral...

Abstract Oral diseases cause a wide range of difficulties for patients. The natural bioactive compound dihydroquercetin (DHQ), which demonstrates regenerative,...

Abstract Background/Objectives: Excipients play a key role in the manufacturability and performance of solid oral dosage forms, particularly for drug...