Solubilizer

Abstract Cyclodextrins (CDs) play a crucial role in pharmaceutical formulations due to their unique ability to form inclusion complexes with a wide range of lipophilic drugs. Ternary complexes comprising CD, water-soluble polymer, and drug molecule have emerged as promising multicomponent to the…
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This poster was presented at the ECP 2025 in Porto Introduction Hot melt extrusion (HME) is generally applied for the formulation of amorphous solid dispersions (ASD) aiming to enhance the solubility of poorly water-soluble drugs . The aim of this work was to evaluate the use of an innovative dry…
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Webinar series by Gattefossé and SeraNovo Gattefossé, a worldwide supplier of lipid-based excipients for the pharmaceutical industry, collaborates with SeraNovo, a leader in proprietary formulation technology designed to enhance the bioavailability of complex molecules, to organize a series of two…
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In the pharmaceutical industry, ensuring the bioavailability of active ingredients is crucial for the effectiveness of orally administered treatments. Bioavailability refers to the proportion of a drug that successfully reaches systemic circulation and its intended therapeutic site after…
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Abstract The flavonoid hesperidin is a crucial, biologically active substance of great interest because of its polypharmacological properties and high safety profile. However, its widespread use of this bioflavonoid in remedies for the treatment and prevention of various diseases is limited by its…
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Abstract This study developed a mucoadhesive self-nano emulsifying drug delivery system (SNEDDS) with synthesized acyl chitosan coating for enhancing oral bioavailability and drug retention of Amphotericin B (AB) which is conventionally administered parenterally owing to its poor bioavailability.…
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Abstract Schistosomiasis, a parasitic disease affecting around 250 million people globally, primarily children, necessitates the urgent development of pediatric praziquantel formulations, as outlined in the WHO neglected tropical diseases roadmap 2021–2030. We developed a low-cost PZQ…
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Abstract Amorphous solid dispersion (ASD) is one of the most studied strategies for improving the dissolution performance of poorly water-soluble drugs, but ASDs often have low drug loadings, thereby necessitating larger dosage sizes. This study intended to create Soluplus® (SOL)-based…
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KLK Kolb excipients, marketed under the Hedjuvan brand, are all produced at the Hedingen facility in Switzerland. These versatile excipients find extensive use in human, veterinary and biopharmaceutical industry. As surfactants, they play a crucial role in surface-to-surface interactions, including…
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AQUAPOL Thickening and gelling agent The AQUAPOL line of “Acrylates polymers” is a synthetic high molecular weight cross-linked water-soluble polymer of acrylic acid. The cosmetic, pharmaceutical, and home industries all use it extensively. It comes as a liquid or powder and is soluble in water,…
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