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Abstract Disintegrant performance in insoluble, poorly disintegrating matrices is strongly influenced by how the excipients are assembled at the granule...
Abstract Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble...
Abstract Minitablets represent a promising oral solid dosage form that allows for a wide range of doses within a single...
This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Calcium Carbonate: A Widely used...
Abstract The low solubility of propolis in water and its limited bioavailability reduce the effectiveness of bioactive compounds, demonstrating the...
Abstract Although solid oral dosage forms are widely used in adult drug therapy, age-appropriate formulations for pediatric patients remain limited....
TopMill, a milled ready-to-use pigment and dye premix, produced tablet cores with no by-eye detectable defects in direct compression trials,...
Abstract Press-coated tablets (PCTs) are a modern dosage form designed to circumvent the negative effects of liquid and heat exposure...
Abstract We developed a headspace gas chromatography method with flame ionization detection (HSGC-FID) for trace nitrite determination in pharmaceutical excipients....
Abstract Lubricants are indispensable in tableting, as their impact extends beyond facilitating ejection to altering compressibility and tablet strength. However,...
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