Inorganic Chemicals

Abstract Previous research has shown that controlled release (CR) formulations with hydrox- ypropyl methylcellulose (HPMC) as hydrophilic matrix former produced via twin-screw wet granulation (TSWG) yield granules with an inhomogeneous active pharmaceutical ingredient (API) distribution (Denduyver…
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Abstract Synthetic apatitic calcium phosphates are widely used to develop biomaterial devices due to their excellent biological properties. The aim of this study was to develop nanocrystalline apatitic calcium phosphates (NCA) bioceramics with tunable porosity (size of pores, total porosity…
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Abstract Tablets are coated for taste or odor modification, for modified release profiles or as a protective layer to increase the stability. Here, titanium dioxide is frequently added as a coating component due to its opaque properties. Furthermore, its Raman activity makes it an integral part…
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Abstract Background/Objectives: The aim of the present study was to develop lactose-free formulations of rivaroxaban, a novel oral anticoagulant used for the treatment and prevention of blood clotting. As a BCS Class II drug, rivaroxaban is characterized by poor solubility in aqueous media, posing…
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Abstract The viability of probiotic microorganisms is essential for their health-promoting effects and must be preserved in the best possible way during the production of the final dosage form, such as tablets. This applies to both drying and tableting. Saccharomyces cerevisiae is spray-dried…
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Abstract Pharmaceutical drug dosage forms are critical for ensuring the effective and safe delivery of active pharmaceutical ingredients to patients. However, traditional formulation development often relies on extensive lab and animal experimentation, which can be time-consuming and costly.…
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Abstract This review investigates the progression and effectiveness of colon-targeted drug delivery systems, offering a comprehensive understanding of the colon's anatomy and physiological environment. Recognizing the distinctive features of the colon is crucial for successfully formulating…
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Abstract Liquisolid systems (LS) represent a formulation approach where liquid drug or its dispersion is transformed into a powder with good flowability and compactibility, leading to enhanced drug dissolution and bioavailability. Many research groups have focused on the preparation and…
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This poster was presented at the DDF Summit Conference 2024 by Valentyn MOHYLYUK, Zoltán Márk HORVÁTH, Kirils KUKULS, Liga LAUBERTE, Artūrs PAULAUSKS from Rīga Stradiņš University: Introduction Replacing batch wet granulation with twin-screw melt extruder as a continuous solventless process is…
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This poster was presented by Galvita at EuPFI 2024 in Rotterdam Introduction Modern drug delivery needs to use novel multifunctional materials for developing medicinal products and new therapies. Porous particles attract a lot of attention as promising drug delivery systems. Functions of porous…
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