Pharma Excipients
Plasticizer
Coatings Portfolio from BASF Pharma Solutions
BASF Pharma Solutions offers film-forming polymers and additive chemistries for your aesthetic, protective, and functional coating needs.
BASF’s Kollicoat® portfolio provides easy-to-use coating options based on your tablet’s needs and desired functionality. Products from our Kolliphor®,…
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Taste Masking of Orodispersible Films: A Case Study in Palatability Optimization
It's all about the taste when David Tisi from Senopsys writes an article and we are happy to share his view on "Taste Masking of Orodispesible Films" with you in this article.
Orodispersible films (ODFs) are strips of water-soluble polymer matrices which contain an active ingredient that dissolves…
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Formulation and Optimization of Fast Dissolving Thin Strips of Desvenlafaxine HCl by Using Quality…
Abstract
Aim
The present work was aimed to formulate and optimize fast dissolving thin strips of Desvenlafaxine Hydrochloride using QbD.
Materials and Methods
The solvent casting method was used to formulate fast dissolving thin strips. The drug (Desvenlafaxine HCl), polymer
(pullulan), super…
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Influence of Plasticizer Selection on the Performance of DRUGCOAT® L 100-55 in Enteric-Coated…
ABSTRACT
Enteric coatings are widely used in pharmaceutical formulations to protect drugs from the acidic environment of the stomach or to prevent gastric irritation caused by certain drugs. This study investigates the influence of different plasticizers on the performance of DRUGCOAT® L 100-55, a…
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Orodispersible films prepared by hot-melt extrusion versus solvent casting
Abstract
This study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional properties of orodispersible films with the same composition and incorporating a poorly soluble active pharmaceutical ingredient (API). Both…
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Thermal Analysis of Lactose Polymorphs – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
Introduction
The following polymorphic forms of lactose exist: α-Lactose Monohydrate (α-LMH), α-Lactose Anhydrous (α-LA) stable, α-LA unstable, β-Lactose Anhydrous (ß-LA) and amorphous Lactose (Lamorph). α-LMH is the thermodynamically most…
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Film-forming solutions for cutaneous application: current challenges and future directions in…
Abstract
Film-forming solution (FFS) implies a novel formulation strategy for liquid preparations for cutaneous application with numerous advantages in comparison with compendial dosage forms, including flexibility of composition (active pharmaceutical ingredient (API) solution in volatile and…
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Extrusion-Based 3D Printing of Pharmaceuticals—Evaluating Polymer (Sodium Alginate, HPC, HPMC)-Based…
Abstract
Three-dimensional printing is promising in the pharmaceutical industry for personalized medicine, on-demand production, tailored drug loading, etc. Pressure-assisted microsyringe (PAM) printing is popular due to its low cost, simple operation, and compatibility with heat-sensitive drugs…
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Hot-melt extruded-FDM 3D-printed polyethylene oxide tablets: Dissolution imaging analysis of…
Abstract
Recent developments in pharmacogenetics have emphasised the importance of customised medication, driving interest in technologies like FDM 3D-printing for tailored drug delivery. FDM 3D-printing is a promising technique for the on-demand manufacturing of customised oral dosage forms,…
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Unveiling tablet structural changes: A micro computed tomography analysis of aqueous coating effects
Abstract
Tablet coating with aqueous solvents represents a well-established environmentally sustainable alternative to coatings based on organic solvents. However, this practice requires a careful evaluation of potential quality issues, such as increased porosity and crack formation stemming from…
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