Excipient for Inhalation

Abstract Inhalable messenger RNA (mRNA) therapeutics provide direct access to the respiratory tract but liquid mRNA-lipid nanoparticle (LNP) formulations often...

Abstract Pulmonary delivery of poorly water-soluble drugs is constrained by the limited volume of epithelial lining fluid, heterogeneous aerosol deposition,...

Abstract As a major public health issue, chronic obstructive pulmonary disease (COPD) causes approximately 2.7 million deaths worldwide each year...

Abstract Capsule aperture geometry is a tunable design parameter that can markedly influence powder emission and aerosol dispersion in capsule-based...

Abstract Inhaled biologics to treat lung diseases have an extensive history. This is counterbalanced by the limited products that have...

Abstract Introduction Globally, lung cancer is one of the most common types of cancer. Despite advances in treatment, the clinical...

Abstract In this paper, the International Pharmaceutical Aerosol Consortium on Regulation and Science (IPAC-RS), discusses the current regulatory landscape associated...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract Background/Objectives: The development of dry powder formulations for pulmonary delivery of therapeutic antibodies requires careful stabilization strategies to preserve...

Abstract Lower respiratory tract infections (LRTIs) constitute the fourth leading cause of mortality worldwide, resulting in over two million deaths...