Pharma Excipients
Suspension Agent
The science of pharmaceutical suspensions explained! – Explainer video by Pharma Drama
In this video Pharma Drama aka Prof. Simon Gaisford explains how suspensions are formulated and what the medicine is trying to achieve in terms of their properties.
See the video and read the full transcript below.
Read the full video transcript here:
Welcome to Pharma Drama, the…
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Skin-friendly textures – by Gattefossé
Caring for patients
Patient preferences and needs as well as therapeutic indication should be considered at early stage of development of topical or transdermal formulations.
To increase adherence to skin treatments, it is important to consider patient’s needs, when designing the dosage…
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Rheology of amino-functionalized graphene oxide suspensions in hydrogels
This work investigates the effects of amino-functionalized graphene oxide (AFGO) suspensions on the rheological behavior of Carbopol® hydrogels at pHs 5, 7, and 9. The AFGO concentration and media pH were evaluated and related to the suspension's microstructure and rheology. Graphene oxide (GO)…
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Long-Acting Injectable Aqueous Suspensions—Summary From an AAPS Workshop
Through many years of clinical application of long-acting injectables, there is clear proof that this type of formulation does not just provide the patient with convenience, but more importantly a more effective treatment of the medication provided. The formulation approach therefore contains huge…
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Cationic nanocapsule suspension as an alternative to the sublingual delivery of nifedipine
Nifedipine (NIFE) is a calcium channel blocker drug used to treat cardiovascular diseases, angina, and hypertension. However, NIFE is photolabile, has a short biological half-life, low aqueous solubility, and undergoes an intense first-pass effect, compromising its oral bioavailability. Thus, this…
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A Review on Taste Masked Multiparticulate Dosage Forms for Paediatric
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous…
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Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles…
Niclosamide is an FDA-approved anthelmintic that is being studied in clinical trials as a chemotherapeutic and broad-spectrum antiviral. Additionally, several other applications are currently in the preclinical stage. Unfortunately, niclosamide is a poorly water soluble molecule, with reduced oral…
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Advanced Formulations/Drug Delivery Systems for Subcutaneous Delivery of Protein-Based…
Multiple advanced formulations and drug delivery systems (DDSs) have been developed to deliver protein-based biotherapeutics via the subcutaneous (SC) route. These formulations/DDSs include high-concentration solution, co-formulation of two or more proteins, large volume injection, protein…
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Omeprazole nanoparticles suspension: development of a stable liquid formulation with a view to…
Omeprazole (OME) is often used to treat disorders associated with gastric hypersecretion in children but a liquid pediatric formulation of this medicine is not currently available. The aim of this study is to develop OME loaded nanoparticles with a view to the obtention of a liquid pharmaceutical…
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Studies on the in vitro ion exchange kinetics and thermodynamics and in vivo pharmacokinetics of the…
The short half-life and bitter taste of carbinoxamine maleate (CAM) lead to poor compliance by pediatric patients who are being treated for allergic rhinitis. To address these issues, carbinoxamine-resin complexes (CRCs) were prepared by ion exchange and then coated with Kollicoat SR 30D. The…
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