A wide variety of pharmaceutical products, including pellets, granules, capsules, powders, and crystals are often coated. The procedure of coating tablets is a complex process that results in the forming of a thin layer around the tablet. This layer is in the range of 20 to 200 μm in thickness, or around 1 to 9% of the initial weight of the tablet.
Pharma Excipients
Coating
Design and development of Fujicalin-based axitinib liquisolid compacts for improved dissolution and…
Abstract
Poor dissolution of axitinib (AXT) limits its effectiveness through the oral route. The present study investigated, prospective of liquisolid (LS) technology to improve dissolution rate and oral bioavailability of AXT to treat renal cell carcinoma. LS compacts were fabricated with PEG…
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Easy Scale-up of Wurster Processes for Pellet Drug Layering and Taste Masking
This poster was presented at the EuPFI 2024 in Rotterdam by Glatt Pharmaceutical Services:
Introduction
➢Bitter tasting active pharmaceutical ingredients (API) for children require effective taste masking.
➢ Pellets are ideal dosage forms:
A pre-defined dose of API can be applied by…
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Deciphering the Role of Plasticizers and Solvent Systems in Hydrophobic polymer coating on…
Abstract
The type of plasticizer and the choice of solvent or co-solvents used for coating of a hydrophilic core can greatly impact the permeability, porosity, and mechanical strength of the polymer film. Although, Ethylcellulose (EC) is an old polymer, it is a polymer of choice for modifying the…
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A Review on Tablet in Tablet for Cancer and Use of Artificial Intelligence (AI)
Abstract
The tablet is the most commonly utilised dosage form because to its stability and high level of acceptance among patients. The film and sugar coatings have a crucial role in enhancing the aesthetic qualities of the tablet, such as colour, texture, mouth feel, and taste masking. Therefore,…
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Clean label ingredients for solid oral dosage forms? Why not!
Ready-to-use ingredient premixes for the manufacturing of clean label products. Natural, organic and free of undesired excipients, such as titanium dioxide, silica, talc, magnesium stearate, palm oil, synthetic colors.
In general, clean label is a consumer driven movement, demanding a return to…
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Eudragit® Polymers Can Help Match Virtually Any Target Release Profile
EUDRAGIT® polymers can be used individually or in combination to match virtually any target release profile including immediate, delayed, sustained, pulsatile, accelerated and zero order release. Standard options per coating layer include the use of a single EUDRAGIT® polymer, or a combination of…
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A Method for the Colorimetric Quantification of Sodium Lauryl Sulphate in Tablets: A Proof of…
Abstract
The deformulation stage of original drug products, which includes the quantification of critical excipients, is crucial for the successful development of generic drug products of solid dosage form. Sodium lauryl sulphate (SLS) belongs to the group of critical excipients due to its…
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Easy, fast and reliable! – Product Overview by Biogrund
Excellent excipient premixes for film coating, sugar-coating, coloring and tableting. Tailor-made & ready-to-use.
Easy, fast and reliable application with BIOGRUND products. For accelerated process times and always reproducible results.
Welcome to BIOGRUND
We assist the pharmaceutical and…
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Reduction of Agglomeration and Production Optimization for Enteric Pellet Coatings – Poster by…
Introduction
Pellets are versatile dosage forms for many actives. To control drug dissolution profiles, they can be prepared with different coatings. Coated multiparticulate systems are known to show less variation in drug release than single unit formulations. Furthermore, dose dumping effects due…
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Sigachi Film Coatings & Polymer Blends – The Shield of Quality, The Sheen of Innovation
Introduction
We are Sigachi, a leading name in the world of Microcrystalline Cellulose (MCC) manufacturing tailored for Pharmaceutical applications. With a global footprint spanning over 50+ countries, Sigachi has been a trusted supplier for over three decades, earning a reputation among top…
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