Coating

The aim of the current study is to optimize the bed fluidized coating process of mini tablets by means of an acoustic levitator. The optimized coating parameters, which have to be set in a fluidized bed reactor, can be determined by means of contactless levitation of a single mini tablet in an…
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The purpose of the study was to develop sustained release tablets containing bisoprolol fumarate and an innovative combination of Precirol ATO5 and hydroxypropyl methylcellulose, in order to conclude upon: properties of pharmaceutical tablet formulations, drug-excipients interactions, evaluate their…
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Process analytical technology (PAT) has become an important factor in design, analysis and control of complex technological processes. In the present study, pellet coating process was monitored using four different PAT approaches, i.e. near-infrared (NIR) spectroscopy, Raman spectroscopy, in-line…
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Oral drug delivery technology is mainly provided in the form of solid oral dosage forms (SODF) that have to be swallowed intact and move throughout the oro-esophageal system to release the drug content in the stomach or intestine. As there is growing evidence for an increasing prevalence of impaired…
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Most pH-sensitive polymer coating studies for potential colonic delivery systems apply multiple layers to protect the active agent from degradation and early release in the stomach and small intestine. This study designed a single-coat pH-sensitive layer for colon-specific delivery with a potential…
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For decades, titanium dioxide (TiO2) has been used as a white pigment due to its very high opacity and brightness. Therefore, it has a wide range of applications, from being a colouring ingredient of pharmaceutical film coating, to food application colouring. On the basis of current discussions on…
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Site-specific colon drug delivery is a practical approach for the treatment of local diseases of the colon with several advantages such as rapid onset of action and reduction of the dosage of the drug as well as minimization of harmful side effects. 5-aminosalicylic acid (5-ASA) is a drug of choice…
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Implication of Quantitative Selection of Each Excipient in Product Development Excipients’ role in designing different dosage forms does not require any introduction. These are the additives that are added to the formulation along with pharmacologically active substance. The main purpose of adding…
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Film coating is a common step in tablet manufacture that can be used to improve product appearance, organoleptic properties, or to facilitate swallowing. Functional film coats can also be used as a part of the product’s stabilisation strategy and to modify or delay drug release. The film coat,…
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There a many reasons for coating of different pharmaceutical products such as pellets, granules, capsules, powders and crystals. In this article, we will concentrate on the film-coating of tablets. The procedure of coating tablets is a complex process that results in the forming of a thin layer…
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