A wide variety of pharmaceutical products, including pellets, granules, capsules, powders, and crystals are often coated. The procedure of coating tablets is a complex process that results in the forming of a thin layer around the tablet. This layer is in the range of 20 to 200 μm in thickness, or around 1 to 9% of the initial weight of the tablet.
Pharma Excipients
Coating
Effect of double coating on microencapsulation of levofloxacin using the particles from…
Abstract
A novel double-coating technique was employed to encapsulate levofloxacin (LVF), a potent antibacterial drug, using the particles from gas-saturated solutions (PGSS) process to achieve extended release. The primary coating utilized glyceryl tristearate (GT), a lipid with a high melting…
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Real-time monitoring of multiparticulate coating processes at industrial-scale using…
Abstract
Optical Coherence Tomography (OCT) has been reported as a promising technology for in-line monitoring of pharmaceutical film-coating processes, providing real-time information on actual tablet coating thicknesses and thickness variability, together enabling correlation modeling of the…
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Influence of Plasticizer Selection on the Performance of DRUGCOAT® L 100-55 in Enteric-Coated…
ABSTRACT
Enteric coatings are widely used in pharmaceutical formulations to protect drugs from the acidic environment of the stomach or to prevent gastric irritation caused by certain drugs. This study investigates the influence of different plasticizers on the performance of DRUGCOAT® L 100-55, a…
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Advances in Pharmaceutical Product Development
Advances in Pharmaceutical Product Development
See the new book, edited by Keerti Jain and Awesh K. Yadav. This book discusses the stages involved in pharmaceutical product development including the importance, requirement, and effect of each stage and process.
Description: It also covers…
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Assessment of the protective potential of coated microparticles in a fluidized bed against the…
Abstract
A strategy to enhance the protective effect of bioactive compounds in spray-dried microparticles is fluidized bed coating. Linseed oil was previously microencapsulated by spray drying using maltodextrin and whey protein as wall materials, and then coated with hydroxypropyl…
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Webinar Next-Gen Film Coatings: Merging Sustainability with Superior Performance
The pharmaceutical and nutraceutical industries have traditionally relied on Hydroxypropyl Methylcellulose (HPMC) and Polyvinyl Alcohol (PVA) as the standard polymers for immediate release coatings for solid oral dosage forms. These polymers are commonplace due to their robustness and…
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Evaluating the flow-enhancing and antistatic properties of excipients in free and salt forms: A case…
Abstract
Powder flow characteristics are crucial for efficient processing and manufacturing in the pharmaceutical industry. The occurrence of tribo-charging, a surface phenomenon where particles acquire an electrical charge due to frictional contacts with other particles or surfaces, poses risks…
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Fabrication of lipid-modified drug nanocrystals loaded injectable hydrogel for breast cancer therapy
Abstract
The current study includes the design of soluplus stabilized, lipid-coated, and fucoidan-oleylamine conjugate modified paclitaxel nanocrystals. The nanocrystals (Lipid-NCs) were about 100 nm, homogeneous, stable and showed improved drug release compared to pure PTX. The nanocrystals were…
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DRUGCOAT – Excellence in Pharma Polymer by Vikram Thermo
Vikram Thermo (India) Limited, was established in the year 1984, near Ahmedabad, Gujarat for manufacturing Di Phenyl Oxide in the name of Vikram Enterprise Private Limited, a pioneer in the manufacturing of DPO. Later on company also entered into the business of developing pharma polymer products -…
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Oral dosage forms for drug delivery to the colon: an existing gap between research and commercial…
Abstract
Oral drug administration is the preferred route for pharmaceuticals, accounting for ~90% of the global pharmaceutical market due to its convenience and cost-effectiveness. This study provides a comprehensive scientific and technological analysis of the latest advances in oral dosage forms…
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