An Update on Pharmaceutical Strategies for Oral Delivery of Therapeutic Peptides and Proteins in Adults and Pediatrics

28. December 2020

While each route of therapeutic drug delivery has its own advantages and limitations, oral delivery is often favored because it...

Co-administration of mini-tablets orlistat and xanthan gum

Anti-obesity effect with reduced adverse effect of the co-administration of mini-tablets containing orlistat and mini-tablets containing xanthan gum: In vitro and in vivo evaluation

28. October 2020

The purpose of this study was to develop an oral dosage form of orlistat for the treatment of obesity with...

Transcutol® P Containing SLNs for Improving 8-Methoxypsoralen Skin Delivery

18. October 2020

Topical psoralens plus ultraviolet A radiation (PUVA) therapy consists in the topical application of 8-methoxypsoralen (8-MOP) followed by the skin...

Nanostructured lipid carriers with curcuminoids

Nanostructured lipid carriers loaded with curcuminoids: Physicochemical characterization, in vitro release, ex vivo skin penetration, stability and antioxidant activity

3. September 2020

Four formulations of nanostructured lipid carriers (NLC) loaded with curcuminoids where prepared, testing two types of solid lipids (Compritol® 888...

Development of solid lipid nanoparticle as carrier of pioglitazone for amplification of oral efficacy

30. March 2020

Pioglitazone (PGL) is a hypoglycemic therapeutic agent used in the treatment of diabetes (type 2). The present research work was...

Drug-carrier binding and enzymatic carrier digestion in amorphous solid dispersions containing proteins as carrier

4. April 2019

In order to further explain the ability of gelatin 50PS and bovine serum albumin (BSA) to generate supersaturation of a...

Case Studies on Lipid Excipients

21. February 2019

If you need technical information and practical tips to formulate with your lipid excipients, Gattefossé has prepared different case studies...

Overview graphic stakeholders for pharmaceutical excipients

Current Developments in Excipient Science – Implication of Quantitative Selection of Each Excipient in Product Development

24. January 2019

Implication of Quantitative Selection of Each Excipient in Product Development Excipients’ role in designing different dosage forms does not require...

3D Printing is already used for pharmaceutical tablets

3D-Printed Isoniazid Tablets for the Treatment and Prevention of Tuberculosis—Personalized Dosing and Drug Release

14. January 2019

The aim of the present work was to produce 3D-printed oral dosage forms with a sufficient drug dose displaying various...

Evolution of the Microstructure of Sustained-release Matrix Tablets during Dissolution and Storage

5. December 2018

Glyceryl behenate based-matrix tablets allowed obtaining a sustained release of theophylline for up to 12 hours. The diluent selected as...

Glycols