Pharma Excipients
Sugars
Optimization of formulation and device design for carrier-based nasal powder of influenza vaccine to…
Abstract
Previously, a nasal powder formulation of the influenza vaccine was proposed to ensure its stability over fifteen months at room temperature and to have sufficient moisture-resistant characteristics to enable handling without special humidity control. In this study, a carrier-based…
Read More...
Read More...
Effects of buffers on spray-freeze-dried/lyophilized high concentration protein formulations
Abstract
Solid-state protein formulations are known to exhibit enhanced storage stability compared to their liquid dosage form counterparts. pH is one of the factors affecting the stability of protein formulations. The pH of protein formulations in the solution could be influenced by the buffer…
Read More...
Read More...
How sugar types and fabrication methods affect palatability in paediatric-friendly oromucosal…
Abstract
Ensuring children adhere to their prescribed medication can be challenging, particularly when a large number of medicines on the market consist of unpalatable drugs and difficult to swallow dosage forms. Sugar-based oromucosal films are easy to administer dosage forms across all age…
Read More...
Read More...
A Review on Tablet in Tablet for Cancer and Use of Artificial Intelligence (AI)
Abstract
The tablet is the most commonly utilised dosage form because to its stability and high level of acceptance among patients. The film and sugar coatings have a crucial role in enhancing the aesthetic qualities of the tablet, such as colour, texture, mouth feel, and taste masking. Therefore,…
Read More...
Read More...
Easy, fast and reliable! – Product Overview by Biogrund
Excellent excipient premixes for film coating, sugar-coating, coloring and tableting. Tailor-made & ready-to-use.
Easy, fast and reliable application with BIOGRUND products. For accelerated process times and always reproducible results.
Welcome to BIOGRUND
We assist the pharmaceutical and…
Read More...
Read More...
Impact of Excipients Blending on Sugar-Stabilized Therapeutic Proteins
Abstract
Sugars have long been used as stabilizing excipients for protein-based therapeutics during the development and production process. Incorporating stabilizing agents, such as sucrose and trehalose into dry formulations is a common strategy approved by the US FDA. However, single-sugar…
Read More...
Read More...
Transdermal Delivery of Pramipexole Using Microneedle Technology for the Potential Treatment of…
Parkinson’s disease (PD) is a debilitating neurodegenerative disease primarily impacting neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a dopamine agonist that is currently available in tablet form. However, individuals with PD commonly encounter difficulties with…
Read More...
Read More...
Medication Lubricants for Oral Delivery of Drugs: Oral Processing Reduces Thickness, Changes…
Abstract
Swallowing oral solid dosage forms is challenging for those who have medication swallowing difficulties, including patients with dysphagia. One option is to mix the drug (whole or crushed) with a thick vehicle (medication lubricant). Previous in vitro studies consistently suggest that…
Read More...
Read More...
Fabrication of Orally Fast Disintegrating Wafer Tablets Containing Cannabis Extract Using Freeze…
Abstract
Introduction: The development of a novel dosage form for cannabis extract is necessary to improve drug delivery
and to also enhance patient convenience.
Methods: Orally fast disintegrating wafer tablets containing cannabis extract, which were prepared using the
freeze drying…
Read More...
Read More...
Colon-targeted delivery systems of budesonide as second-line therapy in inflammatory bowel disease
Abstract
In inflammatory bowel disease (IBD), some parts of the gastrointestinal tract GIT become inflamed, depending on the location of the inflammation, it's divided into two types Crohn's and ulcerative colitis (UC). The local absorption of anti-inflammatory drugs such as budesonide (BUD) at the…
Read More...
Read More...