Pharma Excipients
Sugars
Pickering emulsion gels stabilized by protein and polysaccharide-based particles: A review of…
Abstract
With a far longer stability than traditional emulsions, Pickering emulsion gels (PKEGs)—stabilized by solid particles—have proven highly efficient in a range of applications during recent years. Particles based on proteins or polysaccharides with distinctive amphiphilic structure are…
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Smarter Stabilization for Lipid Nanoparticles: Formulating Biopharmaceuticals with Sucrose
We are glad to present our new webinar in collaboration with our partner Nagase Viita:
Smarter Stabilization for Lipid Nanoparticles: Formulating Biopharmaceuticals with Sucrose
REGISTRATION
Learnings:
Toward Sustainable Excellence: Developing High-Quality Saccharides…
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3D-Printed cannabidiol stent for local treatment of urinary tract infections
Abstract
Urinary tract infections (UTIs) are highly prevalent among women and those assigned female at birth, and frequently necessitate the administration of systemic antibiotics, which contributes to the antibiotic resistance crisis due to overuse and suboptimal patient adherence. This study…
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Effervescent Tablet Preparation by Twin-Screw Melt Granulation with Sorbitol as a Melt Binder
Abstract
Methods: Effervescent granules containing citric acid and sodium bicarbonate were successfully prepared for the first time via TS-MG using a polyol (sorbitol) as a melt binder.
Results: Processing parameters, specifically granulation temperature and screw speed, were systematically…
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A novel orodispersible film load with dual-coated sustained-release microparticles for pediatric…
Abstract
Orodispersible films (ODFs), easy to administer, flexible in dosage, and free of choking and aspiration risks, have drawn widespread attention as pediatric formulations. However, it is a great challenge to endow ODFs with sustained release due to their fast disintegration. Herein, we…
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Injectable-Grade Sucrose Solutions: A Sustainable Innovation in Biopharmaceutical Excipients
Moving Glycoscience Forward
How does the Sucrose SG product’s manufacturing process fit into your company’s strong sustainability commitments?
Our proprietary manufacturing system operates in an environmentally responsible and resource-efficient way. All products in the Solbiote portfolio are…
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Development and characterisation of polymeric solid dispersed systems of hesperidin, obtained by…
Abstract
The flavonoid hesperidin is a crucial, biologically active substance of great interest because of its polypharmacological properties and high safety profile. However, its widespread use of this bioflavonoid in remedies for the treatment and prevention of various diseases is limited by its…
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Machine learning driven acceleration of biopharmaceutical formulation development using Excipient…
Abstract
Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher desired drug substance concentrations. The constraint in drug substance supply and the need for a holistic set of analytical methods means that only a small selection…
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Complete solutions for pharmaceutical and nutraceutical coatings by Roquette
Coatings play a crucial role in enhancing patient compliance and adherence to prescription drugs in the pharmaceutical industry, as well as improving consumer experience for nutraceuticals and over-the-counter (OTC) markets.
Film coating solutions
From masking unpleasant tastes and odors to…
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Effect of formulation composition on trastuzumab stability
Abstract
For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they are often followed by one or more biosimilar products. These biosimilars often differ from the innovator product, as well as from each other, in…
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