Pharma Excipients
Sugars
A novel orodispersible film load with dual-coated sustained-release microparticles for pediatric…
Abstract
Orodispersible films (ODFs), easy to administer, flexible in dosage, and free of choking and aspiration risks, have drawn widespread attention as pediatric formulations. However, it is a great challenge to endow ODFs with sustained release due to their fast disintegration. Herein, we…
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Injectable-Grade Sucrose Solutions: A Sustainable Innovation in Biopharmaceutical Excipients
Moving Glycoscience Forward
How does the Sucrose SG product’s manufacturing process fit into your company’s strong sustainability commitments?
Our proprietary manufacturing system operates in an environmentally responsible and resource-efficient way. All products in the Solbiote portfolio are…
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Development and characterisation of polymeric solid dispersed systems of hesperidin, obtained by…
Abstract
The flavonoid hesperidin is a crucial, biologically active substance of great interest because of its polypharmacological properties and high safety profile. However, its widespread use of this bioflavonoid in remedies for the treatment and prevention of various diseases is limited by its…
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Machine learning driven acceleration of biopharmaceutical formulation development using Excipient…
Abstract
Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher desired drug substance concentrations. The constraint in drug substance supply and the need for a holistic set of analytical methods means that only a small selection…
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Complete solutions for pharmaceutical and nutraceutical coatings by Roquette
Coatings play a crucial role in enhancing patient compliance and adherence to prescription drugs in the pharmaceutical industry, as well as improving consumer experience for nutraceuticals and over-the-counter (OTC) markets.
Film coating solutions
From masking unpleasant tastes and odors to…
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Effect of formulation composition on trastuzumab stability
Abstract
For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they are often followed by one or more biosimilar products. These biosimilars often differ from the innovator product, as well as from each other, in…
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Optimization of formulation and device design for carrier-based nasal powder of influenza vaccine to…
Abstract
Previously, a nasal powder formulation of the influenza vaccine was proposed to ensure its stability over fifteen months at room temperature and to have sufficient moisture-resistant characteristics to enable handling without special humidity control. In this study, a carrier-based…
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Effects of buffers on spray-freeze-dried/lyophilized high concentration protein formulations
Abstract
Solid-state protein formulations are known to exhibit enhanced storage stability compared to their liquid dosage form counterparts. pH is one of the factors affecting the stability of protein formulations. The pH of protein formulations in the solution could be influenced by the buffer…
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How sugar types and fabrication methods affect palatability in paediatric-friendly oromucosal…
Abstract
Ensuring children adhere to their prescribed medication can be challenging, particularly when a large number of medicines on the market consist of unpalatable drugs and difficult to swallow dosage forms. Sugar-based oromucosal films are easy to administer dosage forms across all age…
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A Review on Tablet in Tablet for Cancer and Use of Artificial Intelligence (AI)
Abstract
The tablet is the most commonly utilised dosage form because to its stability and high level of acceptance among patients. The film and sugar coatings have a crucial role in enhancing the aesthetic qualities of the tablet, such as colour, texture, mouth feel, and taste masking. Therefore,…
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