Pharma Excipients
Coating Systems and Additives
A Comprehensive Review on Pharmaceutical Ready premix Coating Powder
Coating is an essential process in the pharmaceutical and nutraceutical industry. Earlier pharmaceutical formulation companies used to buy separate ingredients and mix them for colour coating, but nowadays many manufacturers are involved in making ready premix coating powder and this reduces the…
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Controlling the drug release with functional film coating
Functional film coatings are a topic which considers many formulators. Therefore we gladly share this interesting overview by BIOGRUND.
Definition of “Functional Film Coating”:
A functional film coating has an influence on the drug release and is used to modify the release of the active…
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Minerals as Excipients – Dr. Paul Lohmann
The major component of ingredients in pharmaceutical products in terms of volume is not the active ingredient itself, it is the excipient. Excipients assist in the administration of an ‘active’ substance that typically may not be easily administered or absorbed by the patient.
Mineral Salts as…
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Particle circulation and coating in a Wurster fluidized bed under different geometries
Abstract
The performance of particle coating is essentially determined by the morphology and uniformity of coating shells, which significantly depend on particle circulation. In this study, the geometry of a Wurster fluidized bed is changed by regulating particle circulation port size and nozzle…
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Comparison of Mini-Tablets and Pellets as Multiparticulate Drug Delivery Systems for Controlled Drug…
Mini-tablets made into hard capsules or administered using special dosing units, as well as pellets in hard capsules or compressed into tablets, offer the advantages of multiparticulate drug delivery systems and are suitable for controlled drug release using polymer coatings. Four different kinds of…
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Film Coatings Based on Aqueous Shellac Ammonium Salt “Swanlac® ASL 10” and Inulin for Colon…
Over the past decades, increasing interests took place in the realm of drug delivery systems. Beyond treating intestinal diseases such as inflammatory bowel disease, colon targeting can provide possible applications for oral administration of proteins as well as vaccines due to the lower enzymatic…
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Moisture protection strategies and challenges for solid oral dosages
Protecting moisture sensitive substances from environmental moisture is one of the biggest challenges in the pharmaceutical and nutritional supplements industry. Coating the tablet core with a suitable film coating therefore plays an important role in achieving a sufficient moisture barrier. It…
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MicroCoat™: A Breakthrough in Oral Multiparticulate Formulation Development
Oral multiparticulate systems are often the ‘go to’ solution for flexible dosing, especially in cases where a degree of functionality, such as taste masking or modified release, is required from the formulation. One of the preferred methods of adding functionality to multiparticulates is by fluid…
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How to ensure a successful tablet coating formulation development by using polyvinyl alcohol and…
Purpose
Recent ban of titanium dioxide (TiO2; E171) for the use in food and nutritional supplements (European Commission). The regulation includes a commitment to review the necessity of titanium dioxide as a white colorant in medicinal products1.
It is challenging to find a suitable…
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Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics
Abstract
Colonic drug delivery can facilitate access to unique therapeutic targets and has the potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to the colon requires considered formulation development, as both oral and rectal dosage forms can encounter…
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