Calcium Carbonate

Abstract As it adds so many advantages to the finished formulations, excipient utilised in pharmaceutical dosage forms is a special and important ingredient that is just as important as the API. Improving API absorption and bioavailability, boosting organoleptic characteristics and filling the…
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Abstract Tablets are coated for taste or odor modification, for modified release profiles or as a protective layer to increase the stability. Here, titanium dioxide is frequently added as a coating component due to its opaque properties. Furthermore, its Raman activity makes it an integral part…
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The present study aimed to establish the theoretical qualitative and quantitative formula of a nanoparticle-based dietary supplement suitable for menopause therapy by integrating various herbal active ingredients – e.g. diosgenin – into a nano lipid matrix with vegetable oils. NLCs (nanostructured…
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This study aimed to develop a novel pH-modified nanoparticle with improved solubility and oral bioavailability of poorly water-soluble celecoxib by modifying the microenvironmental pH. After assessing the impact of hydrophilic polymers, surfactants and alkaline pH modifiers on the drug solubility,…
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An industrial case study of attempting to comply with EU regulation 2022/63 Recently, concerns have been raised about the safety of titanium dioxide (TiO2), a commonly used component of pharmaceutical film coatings. The European Union has recently prohibited the application of this material in the…
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Abstract Continuous manufacturing is a novel concept to produce high quality drug products. The manufacture of solid dosage forms starts with the feeding of materials, which is consider a critical step because it could have a high influence on the quality of the final product. Therefore, this unit…
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Abstract Drug loading into mesoporous carriers may help to improve the dissolution of poorly aqueous-soluble drugs. However, both preparation method and carrier properties influence loading efficiency and drug release. Accordingly, this study aimed to compare two preparation methods: formulation…
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The objective of the research was to identify significant variables that impact the porosity-related properties of CaCO3 particles. The Placket–Burman design was employed to screen multiple variables, including pH, molar concentrations of calcium chloride and sodium carbonate, temperature,…
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Abstract Functionalized calcium carbonate (FCC), a novel pharmaceutical excipient, has shown promising properties in the field of oral drug delivery. The current study aimed at evaluating the feasibility of FCC as a carrier for the solidification of self-nanoemulsifying drug delivery systems…
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PRESS RELEASE Oftringen (Switzerland), September 2023 – Manufacturers in the field of pharma and nutraceuticals can step into a new era of uncomplicated and future-proof formulation: With the Omyanutra® range, Suisse mineral expert Omya offers advanced excipients to overcome the challenge of…
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