Pharma Excipients

Carbohydrates

Personalized orodispersible films by hot melt ram extrusion 3D printing

Sep 13, 2018

13. September 2018 This work demonstrates the feasibility of the extemporaneous preparation of maltodextrins orodispersible films (ODF) by hot-melt ram-extrusion 3D printing. This method consists of three simple technological operations which can be also implemented in a pharmacy setting. First,…
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Carbohydrates

A Novel Approach for Dry Powder Coating of Pellets with Ethylcellulose

Feb 19, 2018

19. February 2018 The objective of this study was to assess the efficacy and the capability of a novel ethylcellulose-based dry-coating system to obtain prolonged and stable release profiles of caffeine-loaded pellets. Lauric and…
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Carbohydrates

Lactose oleate as new biocompatible surfactant for pharmaceutical applications

Dez 26, 2017

26. December 2017 Abstract Sugar fatty acid esters are an interesting class of non-ionic, biocompatible and biodegradable sugar-based surfactants, recently emerged as a valid alternative to the traditional commonly employed…
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Erythritol as sweetener?

Dez 6, 2017

06. December 2017 Abstract Erythritol is a naturally abundant sweetener gaining more and more importance especially within the food industry. It is widely used as sweetener in calorie-reduced food, candies, or bakery products.…
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Carbohydrates

Alternative Technologies to Improve Solubility and Stability of Poorly Water-Soluble Drugs

Nov 23, 2017

23. November 2017 The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid dispersions (SD) and inclusion complexes (IC) are two of the most promising strategies to improve the…
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Sugars with different thickening power in high shear granulation

Mai 17, 2017

17. May 2017 Abstract Sugars and sweeteners are common ingredients in foods and also in pharmaceutical industries. They are soluble and sticky ingredients and their processing in granulators may be difficult since they can…
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Melatonin: A Silent Regulator of the Glucose Homeostasis

Apr 20, 2017

20. April 2017 Melatonin: A Silent Regulator of the Glucose Homeostasis Abstract In the human organism, the circadian regulation of carbohydrates metabolism is essential for the glucose homeostasis and energy balance.…
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Carbohydrates

Carbohydrates

Personalized orodispersible films by hot melt ram extrusion 3D printing

A Novel Approach for Dry Powder Coating of Pellets with Ethylcellulose

Lactose oleate as new biocompatible surfactant for pharmaceutical applications

Erythritol as sweetener?

Alternative Technologies to Improve Solubility and Stability of Poorly Water-Soluble Drugs

Sugars with different thickening power in high shear granulation

Melatonin: A Silent Regulator of the Glucose Homeostasis

Sugar Spheres: Improving clinical effectiveness with Multiparticulate drug delivery systems

Evaluation of a Process Relevant Method for Determining the Robustness of Sugar Spheres as a Drug…

Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations