Pharma Excipients
Calcium CarbonateCMC and Croscarmellose Sodium
Foam-Based Drug Delivery Systems for Skin Disorders: A Comprehensive Review
Abstract
Foam-based drug delivery systems signify a significant innovation in dermatology, facilitating improved drug penetration and administration via a gas-liquid dispersion matrix. These formulations have shown considerable promise in the medical, cosmetic, and pharmaceutical fields. Recent…
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A modern strategy for digital real-time release testing in continuous tablet manufacturing
Abstract
The pharmaceutical industry is currently moving away from traditional approaches to quality control with off-line quality tests, limited in-line process monitoring and minimal control strategies towards more sophisticated methods. This transition addresses several critical aspects,…
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Accelerated Medicines Development using a Digital Formulator and a Self-Driving Tableting…
Abstract
Pharmaceutical tablet formulation and process development, traditionally a complex and multi-dimensional decision-making process, necessitates extensive experimentation and resources, often resulting in suboptimal solutions. This study presents an integrated platform for tablet formulation…
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In-situ forming solvent-induced phase inversion (SIPI) implants for controlled drug delivery: role…
In recent years, there has been a surge of research focused on in situ-forming implants as a method of localized drug delivery. Despite advancements, the predominant challenge in situ-forming solvent-induced phase inversion (SIPI) implants is significant burst release which typically occurs within…
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Methodology for rapid development of a continuous loss-in-weight feeding process
The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits higher process efficiency, better process control, reduced footprint, and consistent product quality. Understanding mass…
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Sallyso – Croscarmellose Sodium (CCS) by GANGWAL Healthcare
GANGWAL Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine…
Abstract
Ayahuasca, a traditional psychoactive Amazonian brew, usually contains N,N-dimethyltryptamine (DMT) and β-carboline (harmine, harmaline, tetrahydroharmine) monoamine oxidase inhibitors. However, the pharmacological interactions between these compounds remain incompletely understood. In…
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Formulation and evaluation of atorvastatin calcium trihydrate Form I tablets
Abstract
Solid forms transformations and new crystal structures of an active pharmaceutical ingredient (API) can occur due to various manufacturing process conditions, especially if the drug substance is formulated as a hydrate. The conversion between hydrate and anhydrate forms caused by changes…
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Development and Characterization of a Mucoadhesive System Containing Sodium Carboxymethylcellulose…
Abstract
This research focuses on the development and characterization of a mucoadhesive drug delivery system using sodium carboxymethylcellulose (CMC) as the primary mucoadhesive polymer. The study explores the formulation, optimization, and evaluation of the mucoadhesive properties, drug release…
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The compaction effects of different disintegrants in a formulation of oral mefenamic tablets
Introduction
Super disintegrants are chemically modified version of traditional disintegrants used within tablets to improve the speed of release. The investigation looked at taking three commonly used super disintegrants (SSG, CCS and PVP) and incorporating into an Immediate release formulation.…
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