CMC and Croscarmellose Sodium

Abstract Objectives: Fixed-dose combination tablets containing sitagliptin hydrochloride (SG) and metformin hydrochloride (MF) are a mainstay in the clinical management...

Abstract Background Phenytoin has long been used to accelerate wound healing. The aim of this study is to design, fabricate,...

Abstract The low solubility of propolis in water and its limited bioavailability reduce the effectiveness of bioactive compounds, demonstrating the...

Abstract Background/Objectives: Conventional SeDeM-ODT screening relies on physicochemical properties and endpoint disintegration tests, which may have limited discriminatory power among...

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...

Abstract Novel bitter-taste-masking microparticles for loading in orally disintegrating (OD) tablets have been developed using a mechanical powder processor. Swellable...

Abstract Spray dried dispersion (SDD) is increasingly used in solid dose formulations for poorly soluble active pharmaceutical ingredients (APIs). Dissolution...

Abstract Between 2018 and 2021, losartan was the most often recalled product (24% of total recalls) followed by metformin tablets...

Abstract Objectives: The current study presents a sequential strategy for the development of directly compressible powder formulations relying on Design...