Pharma Excipients
DC excipient
Exploring the Versatility of Pharmaceutical Lactose – From Origins to Applications
Introduction
Pharmaceutical lactose by Amor Pharma is a cornerstone in both the pharmaceutical and food industries, valued for its versatility and beneficial properties. This guide explores its origins, chemical properties, manufacturing processes, and functionalities, providing a thorough…
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PROSOLV® RX 90 – Ready-to-Use, High Functionality Excipient Composite for Direct Compression…
Streamline Your R&D and Production
Introduction
The health science industry faces a wide variety of challenges including increased pressure to:
Reduce costs
Accelerate time to market
Improve product performance
Cope with high demands and tight capacities
Utilize modern…
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Twenty grams in two weeks: Material sparing tablet development of direct compression formulations…
Abstract
Material-sparing tablet development (MSTD) describes an approach to tablet formulation development that uses the active pharmaceutical ingredient's (API) material properties to guide formulation design. The work presented here expands on this methodology and demonstrates its application…
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Application of Lactose Co-Processed Excipients as an Alternative for Bridging Pharmaceutical Unit…
Abstract
Improving the manufacturability of drug formulations via direct compression has been of great interest for the pharmaceutical industry. Selecting excipients plays a vital role in obtaining a high-quality product without the wet granulation processing step. In particular, for diluents which…
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MEGGLE’s MicroceLac® Plus – A new benchmark in tabletability by outperforming conventional DC…
MicroceLac® Plus
The new co-processed Excipient for Direct Compression (DC)
What’s new? What’s special?
MicroceLac® Plus is an innovative addition to the MEGGLE co-processed excipients line, combining 35% alpha-lactose monohydrate and 65% microcrystalline cellulose (MCC) to enhance tablet…
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Direct powder extrusion (DPE) 3D-printing of mini-tablets for preclinical studies in rodents
Abstract
3D printing (3DP) plays a crucial role in accelerating formulation processes and significantly reduces the time needed to transition from concept to prototype. This technology is particularly valuable as it allows researchers to quickly adjust the structure and composition of dosage forms…
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Effect of additives and operating conditions on tablet weight variation: Analysis based on powder…
Abstract
The flowability and compressibility of powders during tableting are crucial for determining the quality of pharmaceutical products. Although silicon compounds are additives that improve compressibility, their type and addition ratio could impair flowability. Therefore, formulation and…
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Preparation, characterisation, and testing of reservoir-based implantable devices loaded with…
Abstract
Multiple sclerosis is a chronic neuroimmunological disorder that causes progressive disability, primarily in young adults. It places a significant burden on healthcare systems due to high medication costs and long-term care needs. Implantable devices offer a promising alternative for…
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Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and…
This poster was presented at the ECP 2025 in Porto
Introduction
Polyols, such as mannitol, sorbitol, and isomalt, are widely used as excipients for tablet direct compression formulations because of their excellent compaction properties, flowability, as well as high and pH independent…
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Comparative analysis of tablet dissolution behavior: Batch vs. Continuous direct compression
Abstract
Continuous manufacturing offers advantages over traditional batch methods, including agility, efficiency, and sustainability. However, transitioning to continuous manufacturing in process development is challenging due to the need for early adoption of industrial-scale equipment.…
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