DC excipient

This study systemically investigated the application of core/shell technique to improve powder compactability. A 28-run Design-of-Experiment (DoE) was conducted to evaluate the effects of the type of core and shell materials and their concentrations on tensile strength and brittleness index. Six…
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Direct compression is not only a topic in continuous manufacturing but in pharmaceutical production in general.  In direct compression the physical characteristics of the excipients have a major impact on the processes ability of the formulation. Topics like flowability, bulk density and particle…
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Direct compression (DC) is the easiest and most cost-effective process for tablet manufacturing, since it only involves blending and compression. However, active pharmaceutical ingredients (API) generally exhibit poor mechanical and micromeritic properties, which necessitate dilution and the use of…
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“How would you like your lactose?” is the first question Armor Pharma will ask you. Armor Pharma's commitment is to listen to customer’s needs, to strive to achieve the same goals and to provide suitable solutions. An especially design a customization tool now available on Armor Pharma's…
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Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. Granulation process transforms fine powders into free-flowing, dust-free granules that are easy…
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Sigachi announced the receipt of “Company of the year - Pharmaceutical in Zee  Business Dare to Dream Award”. The award is under the SME category and is given to companies and entrepreneurs, who excel in their respective fields showing growth and better stakeholder returns than the…
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The characterization of pharmaceutical powders by means of the SeDeM diagram expert system allows developing a database. This database is a useful tool in pre-formulation steps as initial screening for suitable filler excipients. This study compiles the characterization of 21 powdery…
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Content uniformity (CU) is a well-recognized challenge for low-dose direct compression (DC) tablet formulations. Using a dual particle engineering approach that involves a) forming a segregation-resistant drug-carrier composite to improve CU and b) nanocoating HPMC to enhance flowability, we have…
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Increasing patient adherence to medication regimens remains a top priority in the pharmaceutical industry. Simultaneously, consumers/patients are looking for dosage forms that are easy to take and that will not disrupt their everyday “on the go” lifestyle. Orally disintegrating tablets (ODTs) can…
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