DC excipient

PRUV® by JRS Pharma is a tablet lubricant designed for formulations in which other lubricants lead to formulation and/or manufacturing challenges. As opposed to the frequently used lubricant, magnesium stearate, PRUV® offers the following advantages: High degree of API compatibility*…
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Direct compression stands out as the preferred method for tablet preparation, with co-processing being extensively explored and commercially employed for creating directly compressible vehicles. This study aims to synthesize and characterize pregelatinized starch-polyvinylpyrrolidone (PGS-PVP)…
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This case study was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria: INTRODUCTION An increasing number of APIs present stability challenges and corresponding tablets require to be formulated with protective…
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Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical  (PBP) Technology, 18 - 21 March 2024, Vienna, Austria: INTRODUCTION Tablets with stability issues often use mannitol, a stable, water-soluble excipient compatible with most drugs. Direct compression is a…
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Evaluation of a new disintegrant mixture from natural resources Introduction Tablet disintegration is most often required to divide a tablet into suitably small sub-units that facilitate achievement of the desired drug dissolution rate. While semi-synthetic or synthetic super-disintegrants are…
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Most of biopharmaceuticals, in their liquid form, are prone to instabilities during storage. In order to improve their stability, lyophilization is the most commonly used drying technique in the pharmaceutical industry. In addition, certain applications of biopharmaceutical products can be…
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Abstract The rice bran and rice bran wax of the KJ CMU107 rice strain were investigated as potential tablet lubricants in a directly compressed tablet formulation. Stabilized full-fatted rice bran (sFFRB), stabilized defatted rice bran (sDFRB), and rice bran wax (RBW) extracted and purified from…
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Abstract The production of tailored, on-demand drug delivery systems has gained attention in pharmaceutical development over the last few years, thanks to the application of 3D printing technology in the pharmaceutical field. Recently, direct powder extrusion (DPE) has emerged among the…
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Abstract Aim: The research aimed to design the glimepiride self-micro emulsifying drug delivery system (SMEDDS) for increased oral bioavailability in albino mice by assessing hypoglycemic efficacy. Materials and Methods: The optimized liquid SMEDDS (L-SMEDDS) prepared by emulsification of…
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JRS Pharma presented three posters at the 2024 PBP World Meeting in Vienna. This is the third poster: Introduction Currently in the small-molecule therapeutic arsenal around40%oftheactivepharmaceuticalingredients (APIs) are poorly water-soluble with up to 90 % of the APIs in current development…
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