Pharma Excipients
DC excipient
Sallyso – Croscarmellose Sodium (CCS) by GANGWAL Healthcare
GANGWAL Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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LUBRISTAR – Innovation, Quality & Competence in Excipients by Gangwal
Gangwal Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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Investigating the Influence of Crospovidone’s Manufacturer Variability on Dissolution Profiles of…
Abstract
This study examines the influence of crospovidone (CP) manufacturer variability on the dissolution profiles of hydrochlorothiazide (HCTZ) tablets. Four CP batches from different manufacturers were characterized using pharmacopeial and physicochemical tests, including infrared absorption,…
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The compaction effects of different disintegrants in a formulation of oral mefenamic tablets
Introduction
Super disintegrants are chemically modified version of traditional disintegrants used within tablets to improve the speed of release. The investigation looked at taking three commonly used super disintegrants (SSG, CCS and PVP) and incorporating into an Immediate release formulation.…
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Advances in Taste-Masking Strategies for Pediatric Brain-Related Disease Treatments: Focus on…
Abstract
Pediatric treatment of brain-related diseases often requires oral medications, where palatability is crucial for patient adherence and therapeutic success. The unpleasant taste of many drugs, especially those used in neurological or psychiatric conditions, can reduce compliance in…
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Determination of Ribbon Solid Fraction in Roll Compaction using Ibuprofen DC100
Abstract
Process Analytical Technology (PAT) plays a crucial role in the design of today’s manufacturing lines as continuous manufacturing becomes more important. Until now PAT tools to measure the ribbon solid fraction (SFribbon) in-line are not commonly used in roll compaction. The aim of this…
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The impact of glidants on the rheological properties of active pharmaceutical ingredients: A study…
Abstract
Nowadays, most of the newly developed active pharmaceutical ingredients (APIs) consist of cohesive particles with a mean particle size of <100μm, a wide particle size distribution (PSD) and a tendency to agglomerate, therefore they are difficult to handle in continuous manufacturing…
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Fujicalin®: Your Partner in Mitigating Nitrosamine Impurities in Drug Products
This newsletter by Fuji Chemical Industries highlights how Fujicalin®, a low nitrite content Dicalcium Phosphate Anhydrous (DCPA), can support manufacturers in mitigating these risks effectively.
THE ISSUES
The rise of nitrosamines in pharmaceuticals is a significant concern due to their potential…
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Direct Compression Granules for more than just Tableting
With DC granules, Dr. Paul Lohmann® manufactures a product line that is ideally suited for direct tableting for pharmaceutical applications and food supplements.
The Direct Compression Granules product line by Dr. Paul Lohmann® covers Calcium, Magnesium, Iron and Zinc Salts offering lots of…
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Kollidon® SR: Formulation techniques and drug delivery applications
Abstract
Kollidon® SR is one of the recent versatile coprocessed excipients in the formulation of modified release dosage forms. It is prepared by co-spray drying from aqueous dispersions of polyvinylacetate and polyvinylpyrrolidone. This article gives a critical review of the physicochemical…
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