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This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Calcium Carbonate: A Widely used...
Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...
Gasil mesoporous silica grades HP33CP and HP54CP improve flow performance in microcrystalline cellulose formulations and reduced tablet weight variability in...
TopMill, a milled ready-to-use pigment and dye premix, produced tablet cores with no by-eye detectable defects in direct compression trials,...
Abstract Alfuzosin hydrochloride, an α1-adrenergic antagonist used in the treatment of benign prostatic hyperplasia (BPH), was formulated as orodispersible tablets...
Abstract In vitro compatibility assessments are a valuable tool for the early identification of potential drug–vehicle interactions. To standardize such evaluations,...
Why developing sustained release formulations? Why developing sustained release formulations? Sustained release (SR) pharmaceutical formulations are built to deliver a...
FROM CHALLENGE TO TRIUMPH Formulating a 500 mg chewable Vitamin C tablet proved especially difficult due to the ingredient’s poor...
Abstract Background/Objectives: The integration of artificial intelligence (AI) into pharmaceutical development has the potential to accelerate early-stage formulation design. In this...
In oral solid dosage forms, lactose is often described as a filler. This description is accurate, but it can be...
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