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Optimized lipid nanoparticles for pulmonary delivery of CRISPR/Cas9 targeting KRAS G12S in lung cancer
Abstract KRAS G12S mutations in non-small cell lung cancer (NSCLC) remain refractory to current targeted therapies, with few clinical options and...
Continuous droplet freezing enables stable powder formulation of extracellular vesicles for therapeutic applications
Abstract Extracellular vesicles (EVs) hold great promise as a novel therapeutic modality. While their use as certain formulations has been...
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