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Abstract Disintegrant performance in insoluble, poorly disintegrating matrices is strongly influenced by how the excipients are assembled at the granule...
Abstract Minitablets represent a promising oral solid dosage form that allows for a wide range of doses within a single...
Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation...
Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...
Abstract Lactose (LA), the primary carrier in dry powder inhalers (DPIs), often exhibits excessive drug adhesion, which impairs aerosolization. In...
Abstract Punch sticking is a well-recognized and extensively studied challenge in pharmaceutical tablet manufacturing. However, the impact of solid-form impurities...
Abstract Press-coated tablets (PCTs) are a modern dosage form designed to circumvent the negative effects of liquid and heat exposure...
Abstract Alfuzosin hydrochloride, an α1-adrenergic antagonist used in the treatment of benign prostatic hyperplasia (BPH), was formulated as orodispersible tablets...
Abstract As a major public health issue, chronic obstructive pulmonary disease (COPD) causes approximately 2.7 million deaths worldwide each year...
Abstract We developed a headspace gas chromatography method with flame ionization detection (HSGC-FID) for trace nitrite determination in pharmaceutical excipients....
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