Pellet

The patent application US20240139215A1 focuses on the development of controlled release formulations for highly lipophilic physiologically active substances, such as cannabinoids. These substances tend to have high lipid solubility (log P of 4 or more), making them difficult to deliver in a…
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The United States Patent Application US20240024263 focuses on methods of administering gamma-hydroxybutyrate (GHB) in combination with divalproex sodium (DVP), particularly for treating conditions like narcolepsy. The aim is to co-administer these drugs without altering their dosage or efficacy. The…
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The patent US11896572B2, titled “Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics,” outlines a pharmaceutical formulation aimed at optimizing the release and therapeutic effectiveness of gamma-hydroxybutyrate (GHB), a drug used for narcolepsy treatment. The patent…
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The following patent on “Extended-release compositions comprising atomoxetine” employs CELLETS® as starter spheres made of Microcrystalline Cellulose. Please, read below a summary. United States Patent Application 20240299307 focuses on an extended-release formulation of atomoxetine, commonly…
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Abstract Orodispersible films (ODFs) have served as an emerging platform for the delivery of drugs in a convenient way. The production of ODFs with incorporated pellets may still be a challenging process due to problems to obtain proper homogeneity and deteriorating mechanical properties of the…
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The gastro-resistant behaviour of solid self-emulsifying drug delivery systems (S-SEDDS) represents a significant and innovative advancement in delivering poorly soluble drugs. Due to the complexity of these systems and the liquid nature of SEDDS, thorough investigation is essential. This study…
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The following patent on “Extended release compositions comprising pyridostigmine” employs CELLETS® as starter spheres made of Microcrystalline Cellulose. Please, read a summary below. CELLETS Microcrystalline cellulose pellets (Cellets) are highly spherical starter pellets consisting of 100…
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Abstract The present study focused on the use of milk as a novel excipient for the manufacture of pharmaceutical dosage forms specifically designed for the pediatric population. Dairy milks with different fat contents were studied to deliver paracetamol orally. The World Health Organization…
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Abstract Background/Objectives: Coated drug pellets enjoy widespread use in hard gelatine capsules. In heterogeneous pellets, the drug substance is layered onto core pellets. Coatings are often applied to generate a retarded release or an enteric coating. Methods: In the present study, the…
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This poster was presented at the EuPFI Conference 2024 by OnDosis AB: Background & Objective Today, oral solid medicines are often presented as relatively large tablets or capsules at one or a few dose strengths that do not offer the possibility for fine dose adjustments. The possibility to…
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