Polymers

Ashland Press Release who enables release over time? we do. date: July 15-17, 2025 location: Philadelphia, Pennsylvania booth: Booth 312 Ashland solvers’ expertise in controlled release polymers results in tailored release profiles for injectable and oral drugs that meet your requirements for…
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Abstract Aim In this study, we developed a dual pH and time-dependent formulation for targeted colonic release, aiming at minimizing adverse effect and enhancing anticancer efficacy of colchicine in the treatment of colorectal cancer. Article highlights The findings of this study…
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Abstract Vaginal drug delivery has gained significant interest due to its numerous advantages, such as good blood flow, bypassing the first-pass effect, low systemic side effects, and potential for sustained release of pharmaceuticals. Initially targeting contraception and local effects from…
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Abstract Background/Objectives: In this study, we present a green, scalable platform for the production of water-dispersible powders co-encapsulating the lipophilic bioactives curcumin (Cur) and eugenol (Eug) within the amphiphilic polymer Soluplus® (SP) via low-temperature spray drying.…
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BASF Pharma Solutions offers film-forming polymers and additive chemistries for your aesthetic, protective, and functional coating needs. BASF’s Kollicoat® portfolio provides easy-to-use coating options based on your tablet’s needs and desired functionality. Products from our Kolliphor®,…
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Abstract The incorporation of poorly soluble active ingredients, which make up the majority of the molecules in development, into fixed-dose combination (FDC) products can be an efficient method to improve the pharmacokinetic properties of these compounds, as well as reduce the side effects and…
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Abstract Hydrogel-forming microarray patches (MAPs) offer a minimally invasive platform for transdermal drug delivery, enabling systemic absorption of active pharmaceutical ingredients. Unlike dissolving MAPs, which deposit their entire polymer matrix into the skin, hydrogel-forming MAPs remain…
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Abstract The safety of repeated microarray patch (MAP) application is crucial for its development as an innovative drug delivery platform. This study is the first to assess the safety of repeated applications of hydrogel-forming, dissolving, and implantable MAPs over four weeks using miniature…
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Abstract The underlying mechanisms governing amorphous solid dispersions (ASDs) stability are complex and influenced by multiple factors, making it a difficult problem to address comprehensively. The current study investigates how various factors affect the long-term physical stability of ASDs,…
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Abstract Sulpiride, (a model class IV drug) is a central dopamine antagonist, that is commonly used in the treatment of various psychiatric and gastrointestinal conditions. However, its poor aqueous solubility and low oral bioavailability (20-30%) limit its therapeutic efficacy. Electrospun…
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