Alginate excipients are versatile biopolymers derived from various natural sources, primarily seaweed, and have gained significant prominence in the pharmaceutical industry due to their diverse applications. The pharmaceutical industry relies on alginates for their exceptional properties, which include gelling ability, controlled drug release, and biocompatibility.
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Alginates
Rheological and Stability Evaluation of Sodium Alginate as a Pharmaceutical Excipient Under Varying…
The following poster was presented at IPEC Americas Excipient World 2025:
PURPOSE
Sodium alginate, a naturally occurring polysaccharide, serves as a widely utilized pharmaceutical excipient owing to its biocompatibility, biodegradability, non-toxicity, gelling attributes, and capacity to form gels…
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3D-Printed cannabidiol stent for local treatment of urinary tract infections
Abstract
Urinary tract infections (UTIs) are highly prevalent among women and those assigned female at birth, and frequently necessitate the administration of systemic antibiotics, which contributes to the antibiotic resistance crisis due to overuse and suboptimal patient adherence. This study…
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Tailored Biopolymer Capsules for Colon-Specific Drug Delivery: A 3D Printing Perspective
Abstract
The present study aims to develop capsules employing hot melt extrusion (HME) and fused deposition modeling (FDM) three-dimensional (3D) printing approach. The primary objective was to establish a colon drug delivery system (CDDS) based on multiple release mechanisms.
Highlights…
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A porridge-like hydrogel promoted the oral bioavailability of veterinary medicines
Abstract
The administration of veterinary medicines via drinking water or feed ingredients is a widely adopted method in intensive livestock and poultry farming due to its convenience and cost-effectiveness. Among these drugs, antimicrobials are extensively used, with over 70% of global…
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Foam-Based Drug Delivery Systems for Skin Disorders: A Comprehensive Review
Abstract
Foam-based drug delivery systems signify a significant innovation in dermatology, facilitating improved drug penetration and administration via a gas-liquid dispersion matrix. These formulations have shown considerable promise in the medical, cosmetic, and pharmaceutical fields. Recent…
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Alginate Scaffold Containing Triamcinolone Sustained Release Microsphere, Melatonin and Stem Cells…
Abstract
Cartilage self-repair capacity is limited, which makes it difficult to treat the damage. Tissue engineering has been developing toward cartilage repair via delivering cells and medications. Herein, triamcinolone microspheres were used within alginate scaffolds enriched with tricalcium…
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Oral dosage forms for drug delivery to the colon: an existing gap between research and commercial…
Abstract
Oral drug administration is the preferred route for pharmaceuticals, accounting for ~90% of the global pharmaceutical market due to its convenience and cost-effectiveness. This study provides a comprehensive scientific and technological analysis of the latest advances in oral dosage forms…
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Recent progress in pharmaceutical excipients as P-glycoprotein inhibitors for potential improvement…
Abstract
Pharmaceutical excipients such as P-glycoprotein inhibitors can also increase the solubility and affinity of drugs to the intestinal membrane, enhance paracellular pathways and endocyte uptake, and activate lymph transport pathways, thereby increasing the bioavailability of oral drugs.…
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Evaluating Swellable Cross-Linked Biopolymer Impact on Ink Rheology and Mechanical Properties of…
Abstract
Background/Objectives: Interest in 3D printing oral thin films (OTFs) has increased substantially. The challenge of 3D printing is film printability, which is strongly affected by the rheological properties of the ink and having suitable mechanical properties. This research assesses the…
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Extrusion-Based 3D Printing of Pharmaceuticals—Evaluating Polymer (Sodium Alginate, HPC, HPMC)-Based…
Abstract
Three-dimensional printing is promising in the pharmaceutical industry for personalized medicine, on-demand production, tailored drug loading, etc. Pressure-assisted microsyringe (PAM) printing is popular due to its low cost, simple operation, and compatibility with heat-sensitive drugs…
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