Alginate excipients are versatile biopolymers derived from various natural sources, primarily seaweed, and have gained significant prominence in the pharmaceutical industry due to their diverse applications. The pharmaceutical industry relies on alginates for their exceptional properties, which include gelling ability, controlled drug release, and biocompatibility.
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Alginates
Polymeric microspheres redefining the landscape of colon-targeted delivery: A contemporary update
Abstract
During recent times, the delivery of the medications to the colon has seen more interest by the researchers, as it proved to be providing both options for treating local colon-related conditions and a route for systemic delivery of the various other types of medications. For these to…
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Evaluation of Monolayer and Bilayer Buccal Films Containing Metoclopramide
Abstract
The objective of this study was to develop buccal film formulations containing metoclopramide hydrochloride monohydrate (MCP) with and without a backing layer and to evaluate their release properties and physiochemical stability. The crystallization of MCP in the polymer matrix was…
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Formulation, Characterization and In Vitro Evaluation of Mesalamine and Bifidobacterium bifidum…
Mesalamine is a first-line drug for the treatment of inflammatory bowel diseases. However, its premature release associated with marketed formulations leads to adverse effects like gastric trouble, vomiting, and diarrhoea. To minimize these side effects, colon-targeted drug delivery is essential.…
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Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics
Abstract
Pills are a cornerstone of medicine but can be challenging to swallow. While liquid formulations are easier to ingest, they lack the capacity to localize therapeutics with excipients nor act as controlled release devices. Here we describe drug formulations based on liquid in situ-forming…
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A review on natural biopolymers in external drug delivery systems for wound healing and atopic…
Abstract
Despite the advantages of topical administration in the treatment of skin diseases, current marketed preparations face the challenge of the skin's barrier effect, leading to low therapeutic effectiveness and undesirable side effects. Hence, in recent years the management of skin wounds,…
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Some Applications of Arthrospira platensis and Algae in Pharmaceutical and Food Technologies
Abstract
Algae, as well as Arthrospira platensis, have a wide range of biologically active constituents that determine different pharmacological properties. They are also the basis for developing various new nutritional compositions and supplements. This review summarizes the application of algae…
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Biopolymer Packaging Materials in the Pharmaceutical Industry
Biopolymer packaging materials are gaining prominence in the pharmaceutical industry due to environmental concerns. Derived from renewable sources, these biopolymers offer biodegradability, biocompatibility, and non-toxicity, making them ideal for various pharmaceutical applications. In drug…
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Advancing oral drug delivery: The science of fast dissolving tablets (FDTs)
The field of oral drug delivery has witnessed significant advancements, with a focus on developing innovative formulations to address challenges associated with traditional dosage forms, especially for patients with difficulties in swallowing. Fast Dissolving Tablets (FDTs) have emerged as a…
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A Comprehensive Review of Disintegrants: Backbone of disintegration
Abstract
Strong attractive bonding forces works among the particles of solid dosage forms such as mechanical, solid and intermolecular and bioavailability of solid dosage form is preferentially dependent on in vivo disintegration then dissolution. This review is focused for disintegrating agents,…
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Mucoadhesive Vaginal Tablets Containing Metronidazole: Screening of Optimal Natural Polymer in the…
(1) Background: The study aimed to compare the impact of various natural polymers–sodium alginate, acacia gum, carrageenan, guar gum, xanthan gum, and tragacanth on the formulation and the physical properties of mucoadhesive vaginal tablets containing metronidazole (167 mg/g).
(2) Methods: The…
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