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Crospovidone
Effects of omitting titanium dioxide from the film coating of a pharmaceutical tablet
An industrial case study of attempting to comply with EU regulation 2022/63
Recently, concerns have been raised about the safety of titanium dioxide (TiO2), a commonly used component of pharmaceutical film coatings. The European Union has recently prohibited the application of this material in the…
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Advancing oral drug delivery: The science of fast dissolving tablets (FDTs)
The field of oral drug delivery has witnessed significant advancements, with a focus on developing innovative formulations to address challenges associated with traditional dosage forms, especially for patients with difficulties in swallowing. Fast Dissolving Tablets (FDTs) have emerged as a…
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A Comprehensive Review of Disintegrants: Backbone of disintegration
Abstract
Strong attractive bonding forces works among the particles of solid dosage forms such as mechanical, solid and intermolecular and bioavailability of solid dosage form is preferentially dependent on in vivo disintegration then dissolution. This review is focused for disintegrating agents,…
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Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate
Despite major improvements brought about by the introduction of taste-masked formulations of 4-phenylbutyrate (PB), poor compliance remains a significant drawback to treatment for some pediatric and dysphagic patients with urea cycle disorders (UCDs). This study reports on the development of a…
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Solidifying Fenofibrate Nanocrystal Suspension: A Scalable Approach via Granulation Method
The pharmaceutical industry has highlighted particle-size reduction via preparing aqueous suspensions containing nano- or submicron drug particles. Owing to the risk of agglomeration and complications during the manufacturing of solid dosage forms, the problems associated with the solidification of…
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Formulation and Characterization of Bilastine Oral Disintegrated Tablets Using Natural and Synthetic…
Bilastine (BLS) is a second-generation H1- antihistamine that is approved recently for the symptomatic treatment of chronic urticaria. The present investigation was to develop oral disintegrating tablets of BLS to produce a fast onset of action. In this study, an attempt was made to compare the…
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Effect of Croscarmellose Sodium in Sustained Release Layer of Valsartan in Bilayer Tablet with…
The aim of the study was to design and evaluate bilayer tablets of clopidogrel as immediate release and quick relief and valsartan for sustained release and check the effect of croscarmellose sodium (2%) in Carbopol for sustained release action. Bilayer tablets was prepared using direct compression…
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Effect of Powdered Cellulose Nanofiber with Different Particle Sizes on the Physical Properties of…
Abstract
Direct compression is a tableting technique that involves a few steps in non-demanding manufacturing conditions. High strength and rapid disintegration of tablet formulations were previously achieved through the addition of cellulose nanofibers (CNFs), which have recently attracted…
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Revolutionary Advancements in Fast Dissolving Tablets: An In-Depth Exploration
ABSTRACT
A novel drug delivery system plays a pivotal role in enhancing patient adherence to medication regimens. Among these innovative approaches, fast dissolving tablets (FDT’s) stand out as a particularly promising option. FDT’s offer a range of benefits, including precise dosing, ease of…
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A Shrewd Ingenious Approach of Oral Drug Delivery of Insulin for the Amelioration of Diabetic…
Since 1922, insulin has saved the lives of countless people. However, the difficulties of subcutaneous administration, the need for frequent glucose self-monitoring, and the non-physiological action profiles of insulin prompted many medical professionals and patients to ask fornon-injectable insulin…
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