Crospovidone

Abstract Liquisolid systems (LSS) represent a promising approach for improving dissolution of poorly water-soluble drugs; however, the interplay between formulation...

Abstract Background/Objectives: Conventional SeDeM-ODT screening relies on physicochemical properties and endpoint disintegration tests, which may have limited discriminatory power among...

Abstract Alfuzosin hydrochloride, an α1-adrenergic antagonist used in the treatment of benign prostatic hyperplasia (BPH), was formulated as orodispersible tablets...

Abstract Purpose This study aimed to optimize a high-shear hot-melt granulation process for the development of tinidazole 500 mg tablets while...

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Abstract Digital design of multi-component pharmaceutical tablets based on the properties of individual constituents plays a critical role in the...

Abstract A gastro-retentive drug delivery system based on a tablet-integrated superporous hydrogel (SPH) was developed using Famotidine as a model...

Abstract Background/Objectives: For hyperlipidemic patients with statin resistance, a fixed-dose combination of a non-statin drug such as ezetimibe (EZT) and...

Abstract Background/Objectives: The development of extended-release oral dosage forms remains a complicated and time consuming process, particularly during early formulation...