Cyclodextrin

Abstract Background: The key parameters determining the bioavailability of an active pharmaceutical ingredient are its solubility/dissolution rate in physiological fluids...

Abstract Background/Objectives: Inclusion complexes among drugs and cyclodextrin-modified polymers are a topic of recent interest in pharmaceutical research and industry...

Abstract Protein-based drugs are precise therapeutic options for various refractory lung diseases, significantly improving patient prognosis and quality of life....

Abstract The inclusion complex formed between hydrocortisone and β-cyclodextrin was successfully obtained and structurally characterized in the solid state. Single-crystal...

Abstract The current study aims to develop a polymer hybrid scaffold functionalized with Eudragit nanoparticles, having an inherent effect on bone tissue...

Abstract Dextrin-based nanosponges (D-NS) are promising candidates for oral drug delivery due to their biocompatibility, mucoadhesive properties, and tunable swelling...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent...

This study explores the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its physical properties, thermal...

Abstract The pronounced bitterness of herbal mother tinctures often limits their palatability, despite their therapeutic value. This study evaluates the...

Abstract Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows...