Cyclodextrin

Abstract Poor aqueous solubility is a major cause of solubility-limited absorption and misleading pharmacokinetic outcomes during early oral drug discovery....

Abstract Spray freeze-drying (SFD) is a cutting-edge technique for producing dry powders, ideal for pulmonary drug delivery, owing to its...

Abstract Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal...

Abstract Propolis is a widely studied natural raw material, the composition of which varies depending on the plant origin, harvest...

Abstract The beneficial effect of bedaquiline fumarate (BQF) for tuberculosis (TB) is limited by its oral bioavailability, which is very...

AI in pharmaceutical drug product design is, in 2026, a decision-support technology, not autonomous formulation. The most mature tools combine...

Abstract Entacapone is a catechol-O-methyltransferase (COMT) inhibitor, widely used for the symptomatic treatment of Parkinson’s disease. However, it presents setbacks...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract Objectives: Tolvaptan is a compound that is practically insoluble in water and poorly soluble at physiological pH, and is...

Abstract The taste of a drug formulation, especially of orodispersible and liquid dosage forms, is of crucial importance due to...