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Drug Delivery
3D Printing in Oral Drug Delivery: Technologies, Clinical Applications and Future Perspectives in…
Abstract
The recent advancement of 3D-printed drugs is an emerging technology that has the potential for effective and safe oral delivery of personalized treatment regimens to patients, replacing the current “one size fits all” philosophy. The objective of this literature review is to highlight the…
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Hydroxypropyl Methylcellulose—A Key Excipient in Pharmaceutical Drug Delivery Systems
Abstract
Hydroxypropyl methylcellulose (Hypromellose, HPMC) is a well-known excipient used in the pharmaceutical and nutraceutical fields due to its versatile physicochemical properties. HPMC (derived from cellulose and obtained through etherification) varies in polymerization degree and viscosity,…
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Degradable Hydrogel Microspheres for Drug Delivery: In Vitro Performance and Influence of E-Beam…
Abstract
The present work examines the in vitro drug delivery performance of degradable microspheres (DrugMic) composed of a crosslinked hydrogel of poly(ethylene glycol), with particular interest on the effect of e-beam sterilization on the stability of loaded active substances, i.e. niflumic acid…
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Evaluating the potential of ultrasound-assisted compression for crafting implantable drug delivery…
Abstract
This study aimed to evaluate the feasibility of using ultrasound-assisted compression (USAC) for manufacturing implantable drug delivery systems (IDDS). USAC integrates the principles of traditional compression techniques with the application of ultrasound waves. The combined mechanical…
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Enzymatic absorption promoters for non-invasive peptide delivery
Abstract
Peptide drugs offer considerable potential for treating a diverse range of diseases. Yet, their clinical application is generally restricted to injectable therapies. The main challenge hindering their broader use through globally accessible, patient-friendly, and non-invasive delivery…
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A drug delivery perspective on nanotechnology-based topical therapeutics for inflammatory skin…
Abstract
Inflammatory skin diseases are chronic conditions that significantly affect patients’ skin health and quality of life. Traditional treatments, including systemic immunosuppressants and topical therapies, often face limitations such as low efficacy, inadequate skin penetration, and severe…
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Hydrogels in Drug Delivery – Part 2
Hydrogels in Drug Delivery
See the new book, edited by Alejandro J. Paredes, Garry Laverty, Eneko Larrañeta, Ryan F. Donnelly. It covers the fundamental mechanisms of drug delivery from a hydrophilic matrix, breaks down interconnections between introductory theory and applied materials chapters and…
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Hydrogels in Drug Delivery – Part 1
Hydrogels in Drug Delivery
See the new book, edited by Alejandro J. Paredes, Garry Laverty, Eneko Larrañeta, Ryan F. Donnelly. It covers the fundamental mechanisms of drug delivery from a hydrophilic matrix, breaks down interconnections between introductory theory and applied materials chapters and…
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Development and optimization of lyophilized dry emulsion tablet for improved oral delivery of…
Abstract
Ivermectin (IVM) is a widely used antiparasitic agent and has been repurposed for the treatment of COVID-19. However, its poor water solubility and low bioavailability present significant challenges, often requiring large doses for therapeutic effectiveness. This poses a burden on…
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Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Abstract
Intraoral delivery of active pharmaceutical ingredients (API) is an attractive approach to improve their local therapeutic efficacy or to enable their systemic delivery. It offers several advantages, such as high drug concentration at the intraoral target site and rapid access to the…
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