Drug Delivery

Abstract Background/Objectives: The aim of this study was to develop and apply a novel integrated approach for predicting local mucosal tolerability...

Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...

Abstract Background: Lipid nanoparticles are widely investigated as oral drug delivery systems, but their intestinal performance remains difficult to predict based...

New formulation strategies are beginning to yield clinically and commercially viable oral biological therapies, according to a Lonza whitepaper published...

Abstract Cannabidiol (CBD) exhibits poor oral bioavailability (approximately 6%) due to low solubility and excessive first-pass metabolism, limiting its therapeutic...

Abstract 3D printing has emerged as a novel technology for producing personalized dosage forms tailored to patients’ therapeutic needs. Hot-melt...

Abstract The dynamic and transitory nature of the distal small intestine makes targeted drug delivery to this region particularly challenging....

Abstract This study explores the development of a self-nanoemulsifying drug delivery system (SNEDDS) to enhance the biopharmaceutical profile of lornoxicam,...

Abstract Purpose Simvastatin (SIM) is a widely prescribed lipid-lowering agent; however, its clinical efficacy is hindered by poor aqueous solubility...

Compressol™ ProTab Offering superior compactability for high dose / difficult to compress actives combined with the ability to protect fragile...